John M. Asara

Beth Israel Deaconess Medical Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

115h-index60.0kcitations830works2.32yr avg
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Research Topics

Cancer, Hypoxia, and Metabolism(138), RNA modifications and cancer(100), Epigenetics and DNA Methylation(69), Lung Cancer Treatments and Mutations(65), PI3K/AKT/mTOR signaling in cancer(59)

Publications830 total

The Effect of Dasatinib on Mechanobiology of Lung Cancer Cells During Metastasis
Fondren Library·2026Open Access
Loss of miR-29a/b1 cluster reprograms the tumor microenvironment and contributes to immunosuppression in lung cancer
Cancer Immunology Research·2026
Abstract B031: Exploring CDKN2A mediated metabolic alterations as an immunotherapy resistance mechanism in non-small cell lung cancer
Cancer Immunology Research·2026
TTF-1 expression in lung adenocarcinoma: clinicopathologic, genomic, and immunophenotypic correlates and outcomes to immunotherapy-based treatments and KRASG12C inhibitors
Journal of Thoracic Oncology·2026
Modeling tissue-specific Drosophila metabolism identifies high sugar diet-induced metabolic dysregulation in muscle at reaction and pathway levels
Nature Communications·2026Open Access
Autopalmitoylation of IDH1-R132H regulates its neomorphic activity in cancer cells
Nature Chemical Biology·2026
Lipid scavenging by the Lyme disease spirochete Borrelia burgdorferi
PLoS Pathogens·2025Open Access
Figure S4 from LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma
2025Open Access
Figure S7 from LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma
2025Open Access
Figure S2 from LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma
2025Open Access
Figure S6 from LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma
2025Open Access
Figure S3 from LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma
2025Open Access
Figure S8 from LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma
2025Open Access
Figure S1 from LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma
2025Open Access
Figure S5 from LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma
2025Open Access
Metabolic pathway competition sensitizes thioredoxin reductase-depleted <i>Candida albicans</i> to cell wall stress and antifungals
2025· 1 citedOpen Access
The CTLH ubiquitin ligase substrates ZMYND19 and MKLN1 negatively regulate mTORC1 at the lysosomal membrane
Nature Communications·2025Open Access
Mitochondrial metabolic rewiring sensitizes mTORC1 inhibitor persister cells to cuproptosis
JCI Insight·2025· 1 citedOpen Access
The SLC1A1/EAAT3 dicarboxylic amino acid transporter is an epigenetically dysregulated nutrient carrier that sustains oncogenic metabolic programs
Nature Communications·2025· 1 citedOpen Access
Targeted destruction of VISTA boosts anti-tumor immunotherapy
Cell Research·2025Open Access
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Frequent Co-authors

Lewis C. Cantley(23), Costas A. Lyssiotis(11), Matthew G. Vander Heiden(7), Jason W. Locasale(6), Edouard Mullarky(5), Min Yuan(5), Haoqiang Ying(4), Alec C. Kimmelman(4), Ronald A. DePinho(4), Ng Shyh‐Chang(4), Marcia C. Haigis(4), Brendan D. Manning(4), William S. Lane(3), Lynda Chin(3), Jason B. Fleming(3), Florian L. Müller(3), Dimitrios Anastasiou(3), Susanne B. Breitkopf(3), Christian M. Metallo(3), Heather R. Christofk(3)