Tomasz Cierpicki

University of Michigan–Ann Arbor — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

50h-index7.6kcitations320works7.12yr avg
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Research Topics

Protein Degradation and Inhibitors(69), Acute Myeloid Leukemia Research(45), Cancer-related gene regulation(45), Epigenetics and DNA Methylation(43), Ubiquitin and proteasome pathways(43)

Publications320 total

Supplementary Table S3 from Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia
2025Open Access
Supplementary Table S4 from Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia
2025Open Access
Supplementary Table S2 from Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia
2025Open Access
Supplementary Table S1 from Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia
2025Open Access
Supplementary Figure S1-S8 from Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia
2025Open Access
Supplementary Table S5 from Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia
2025Open Access
Discovery and Development of a Small-Molecule Inhibitor Targeting the GAS41 YEATS Domain in Nonsmall Cell Lung Cancer
Journal of Medicinal Chemistry·2025· 1 citedOpen Access
Abstract 449: Small molecular inhibitors of PRC1 demonstrate potent activity in acute leukemia models
Cancer Research·2025
Targeting Protein–Protein Interactions in Hematologic Malignancies
Annual Review of Pathology Mechanisms of Disease·2025· 4 citedOpen Access
Development of PRC1 Inhibitors Employing Fragment-Based Approach and NMR-Guided Optimization
Journal of Medicinal Chemistry·2025· 4 citedOpen Access
Structure-Based Development of Novel Spiro-Piperidine ASH1L Inhibitors
Journal of Medicinal Chemistry·2024· 2 citedOpen Access
Unlocking the potential of the thioamide group in drug design and development
Future Medicinal Chemistry·2024· 2 citedOpen Access
Menin Inhibitors: Discovery, Development and Clinical Translation
2024
Ziftomenib in relapsed or refractory acute myeloid leukaemia (KOMET-001): a multicentre, open-label, multi-cohort, phase 1 trial
The Lancet Oncology·2024· 68 cited
Drug-resistant menin variants retain high binding affinity and interactions with MLL1
Journal of Biological Chemistry·2024· 11 citedOpen Access
Thioamides in medicinal chemistry and as small molecule therapeutic agents
European Journal of Medicinal Chemistry·2024· 28 citedOpen Access
Combination of menin and kinase inhibitors as an effective treatment for leukemia with NUP98 translocations
Leukemia·2024· 18 citedOpen Access
A Lipopeptidomimetic of Transcriptional Activation Domains Selectively Disrupts the Coactivator Med25 Protein–Protein Interactions
Angewandte Chemie·2024Open Access
A Lipopeptidomimetic of Transcriptional Activation Domains Selectively Disrupts the Coactivator Med25 Protein–Protein Interactions
Angewandte Chemie International Edition·2024· 4 citedOpen Access
Characterization Of Fish And Reptilian Parvalbumins As Relevant Food Allergens
Journal of Allergy and Clinical Immunology·2024Open Access
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Frequent Co-authors

Jolanta Grembecka(29), Trupta Purohit(11), John H. Bushweller(10), Hongzhi Miao(9), Katarzyna Kempińska(7), Shihan He(6), Jacek Otlewski(6), Dmitry Borkin(6), Duxin Sun(6), Ivan Maillard(6), Jonathan Pollock(5), Bo Wen(5), Szymon Kłossowski(5), Hyo Je Cho(5), Shirish Shukla(5), Marcelo J. Murai(4), Mónica L. Guzmán(4), Brian M. Linhares(4), Yali Dou(4), Thomas Hartley(3)