Michael K. Chan

Chinese University of Hong Kong — Hong Kong

Chemistry · Physical Sciences

44h-index6.9kcitations149works1.72yr avg
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Research Topics

Metal-Catalyzed Oxygenation Mechanisms(17), Photosynthetic Processes and Mechanisms(15), Metalloenzymes and iron-sulfur proteins(13), Click Chemistry and Applications(12), Peptidase Inhibition and Analysis(12)

Publications148 total

An engineered yeast cytosine deaminase with improved catalytic activity and stability for macrophage-mediated enzyme/prodrug therapy
Communications Biology·2025Open Access
Can a Diet, Nutrition and Supplement Program Prevent Uterine Fibroid Recurrence? Pilot Results of the LIFE Program
Reproductive Sciences·2025· 1 cited
A Simple Strategy for Co‐Immobilization of NADH‐Dependent Enzymes and NADH for Efficient Biocatalysis in Continuous Flow Reactors
ChemSusChem·2025· 2 citedOpen Access
Development of Nanomolar Affinity Miniprotein Inhibitors Targeting α-Synuclein Aggregation as Promising Therapeutic Agents for Parkinson’s Disease
CCS Chemistry·2025· 1 citedOpen Access
Gene delivery of SUMO1-derived peptide rescues neuronal degeneration and motor deficits in a mouse model of Parkinson’s disease
Molecular Therapy·2025· 2 cited
Site-specific <i>in vivo</i> protein SUMOylation <i>via</i> translational incorporation of a proximity-reactive pyrrolysine analogue
RSC Chemical Biology·2025Open Access
High Throughput Phage Display Screening Identified Peptide Inhibitors Targeting the α-Synuclein for Parkinson’s Disease Treatment
2024Open Access
A Targeted and Protease-Activated Genetically Encoded Melittin-Containing Particle for the Treatment of Cutaneous and Visceral Leishmaniasis
ACS Applied Materials & Interfaces·2024· 2 citedOpen Access
Mechanoresponsive Protein Crystals for NADH Recycling in Multicycle Enzyme Reactions
Journal of the American Chemical Society·2024· 7 citedOpen Access
Genetically Encoded Multienzyme Particles for the Biosynthesis of Putrescine from <scp>l</scp>-Arginine
ACS Sustainable Chemistry & Engineering·2024· 2 citedOpen Access
Amniotic fluid embolism: a reappraisal
Journal of Perinatal Medicine·2023· 3 cited
Predicting COVID-19 Severity Using a Cut-and-Solve Feature Selection Approach
2023
A Bioresponsive Genetically Encoded Antimicrobial Crystal for the Oral Treatment of <i>Helicobacter Pylori</i> Infection
Advanced Science·2023· 8 citedOpen Access
Pyrrolysine-Inspired in Cellulo Synthesis of an Unnatural Amino Acid for Facile Macrocyclization of Proteins
Journal of the American Chemical Society·2023· 13 citedOpen Access
Water-Immiscible Coacervate as a Liquid Magnetic Robot for Intravascular Navigation
Journal of the American Chemical Society·2023· 21 cited
Insights into pyrrolysine function from structures of a trimethylamine methyltransferase and its corrinoid protein complex
Communications Biology·2023· 11 citedOpen Access
Insights from the Structure of an Active Form of Bacillus thuringiensis Cry5B
Toxins·2022· 6 citedOpen Access
Restoration of p53 activity via intracellular protein delivery sensitizes triple negative breast cancer to anti-PD-1 immunotherapy
Journal for ImmunoTherapy of Cancer·2022· 32 citedOpen Access
xSCYTE: Express Single-frame Cytometer through Tomographic Phase
arXiv (Cornell University)·2022· 18 citedOpen Access
Cry3Aa*SpyCatcher Fusion Crystals Produced in Bacteria as Scaffolds for Multienzyme Coimmobilization
Bioconjugate Chemistry·2022· 11 citedOpen Access
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Frequent Co-authors

Bing Hao(10), William H. Armstrong(9), Weimin Gong(7), Marianne M. Lee(7), Tomasz Fekner(6), Joseph A. Krzycki(5), George W. Teebor(5), Douglas C. Rees(4), Robert J. Boorstein(4), Bradley S. Heater(4), Gang Zhao(3), Patrick T. Kang(3), Sunney I. Chan(3), Dina R. Marenstein(3), Joseph W. Arndt(3), Xin Li(3), Alvin Altamirano(3), Ashis K. Basu(3), Richard P. Cunningham(3), Arnulf Kletzin(2)