Christopher McCann

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index647citations59works0.42yr avg
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Research Topics

Cell death mechanisms and regulation(10), Ovarian cancer diagnosis and treatment(7), Cancer-related Molecular Pathways(6), Endometrial and Cervical Cancer Treatments(6), Uterine Myomas and Treatments(6)

Publications58 total

Figure 5 from Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists
2025Open Access
Figure 4 from Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists
2025Open Access
Figure 3 from Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists
2025Open Access
Figure 2 from Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists
2025Open Access
Figure 1 from Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists
2025Open Access
Mitochondrial metabolism is a key determinant of chemotherapy sensitivity in Colorectal Cancer
2024· 3 citedOpen Access
Outpatient blinatumomab with digital monitoring in patients with measurable residual disease positive (MRD+) B-ALL in a phase 4 study.
Journal of Clinical Oncology·2024
Supplementary Figure from Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists
2023Open Access
Supplementary Data from Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists
2023Open Access
Supplementary Data from Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists
2023Open Access
Supplementary Figure from Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists
2023Open Access
Data from Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists
2023Open Access
Data from Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists
2023Open Access
Rerouting the drug response: Overcoming metabolic adaptation in KRAS-mutant cancers
Science Signaling·2022· 10 cited
Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists
Research Portal (Queen's University Belfast)·2022· 3 citedOpen Access
Physiological deterioration in the Emergency Department: The SNAP40-ED study
Emergency Care Journal·2021· 1 citedOpen Access
ALL-071: A Phase 4 Study to Evaluate Outpatient Blinatumomab in Patients with Minimal/Measurable Residual Disease (MRD) Positivity (+) of B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)
Clinical Lymphoma Myeloma & Leukemia·2021
Poster: ALL-071: A Phase 4 Study to Evaluate Outpatient Blinatumomab in Patients with Minimal/Measurable Residual Disease (MRD) Positivity (+) of B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)
Clinical Lymphoma Myeloma & Leukemia·2021
Clinical Positioning of the IAP Antagonist Tolinapant (ASTX660) in Colorectal Cancer
Molecular Cancer Therapeutics·2021· 27 citedOpen Access
Metabolic Reprogramming: A Friend or Foe to Cancer Therapy?
Cancers·2021· 25 citedOpen Access
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Frequent Co-authors

Daniel B. Longley(23), Nyree Crawford(16), Simon S. McDade(15), Katherine McAllister(14), Jochen H.M. Prehn(13), John O. Schorge(10), Andrea Lees(10), Mark Wappett(9), David M. Boruta(8), Vera Grinkevitch(8), Stacey Price(8), Jamie Young(8), Jess Bateson(8), Lewis Gallagher(8), Magali Michaut(8), Aikaterini Chatzipli(8), Syd Barthorpe(8), Daniel Ciznadija(8), Ido Sloma(8), Amy Wesa(8)