Lawrence E. Stramm

Eli Lilly (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

17h-index3.2kcitations35works0.02yr avg
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Research Topics

Retinal Development and Disorders(10), Lysosomal Storage Disorders Research(7), Retinal Diseases and Treatments(6), Glaucoma and retinal disorders(5), Proteoglycans and glycosaminoglycans research(4)

Publications32 total

Design and synthesis of a novel series of [1-(4-hydroxy-benzyl)-1H-indol-5-yloxy]-acetic acid compounds as potent, selective, thyroid hormone receptor β agonists
Bioorganic & Medicinal Chemistry Letters·2015· 9 citedOpen Access
Threonine phosphorylations induced by RX-871024 and insulin secretagogues in βTC6-F7 cells
American Journal of Physiology-Endocrinology and Metabolism·1999· 4 cited
Characterization of a Mutant Pancreatic eIF-2α Kinase, PEK, and Co-localization with Somatostatin in Islet Delta Cells
Journal of Biological Chemistry·1999· 56 citedOpen Access
Assignment<footref rid="foot01"><sup>1</sup></footref> of pancreatic eIF-2α kinase (EIF2AK3) to human chromosome band 2p12 by radiation hybrid mapping and in situ hybridization
Cytogenetic and Genome Research·1999· 7 cited
Identification and Characterization of Pancreatic Eukaryotic Initiation Factor 2 α-Subunit Kinase, PEK, Involved in Translational Control
Molecular and Cellular Biology·1998· 767 citedOpen Access
Abnormalities of retinal metabolism in diabetes or experimental galactosemia: V. Relationship between protein kinase C and ATPases.
Diabetes·1998· 105 cited
Diseases of the Retinal Pigment Epithelium-Photoreceptor Complex in Nonrodent Animal Models
ScholarlyCommons (University of Pennsylvania)·1998· 9 citedOpen Access
Prevention of Vascular and Neural Dysfunction in Diabetic Rats by C-Peptide
Science·1997· 343 cited
Comparison of ELISA and TLC for the Analysis of Promoter Activity When Using the CAT Reporter Gene
BioTechniques·1996· 3 citedOpen Access
Amelioration of Vascular Dysfunctions in Diabetic Rats by an Oral PKC β Inhibitor
Science·1996· 1.1k cited
(<i>S</i>)-13-[(Dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16,21-dimetheno- 1<i>H</i>,13<i>H</i>-dibenzo[<i>e</i>,<i>k</i>]pyrrolo[3,4-<i>h</i>][1,4,13]oxadiazacyclohexadecene-1,3(2<i>H</i>)-dione (LY333531) and Related Analogues:  Isozyme Selective Inhibitors of Protein Kinase Cβ
Journal of Medicinal Chemistry·1996· 336 citedOpen Access
Hepatic Storage of Glycosaminoglycans in Feline and Canine Models of Mucopolysaccharidoses I, VI, and VII
Veterinary Pathology·1992· 39 cited
Glycosaminoglycan and collagen metabolism in arylsulfatase B-deficient retinal pigment epithelium in vitro.
PubMed·1991· 3 cited
Chapter 7 The RPE: A model system for disease expression and disease correction
Progress in Retinal Research·1991· 6 cited
β-Glucuronidase mediated pathway essential for retinal pigment epithelial degradation of glycosaminoglycans. Disease expression and in vitro disease correction using retroviral mediated cDNA transfer
Experimental Eye Research·1990· 74 cited
Restoration of normal lysosomal function in mucopolysaccharidosis type VII cells by retroviral vector-mediated gene transfer.
Proceedings of the National Academy of Sciences·1990· 67 citedOpen Access
Retinal pigment epithelial glycosaminoglycan metabolism: intracellular versus extracellular pathways. In vitro studies in normal and diseased cells.
PubMed·1989· 19 cited
Is rhodopsin the ligand for receptor-mediated phagocytosis of rod outer segments by retinal pigment epithelium?
Experimental Eye Research·1988· 19 cited
Synthesis and secretion of glycosaminoglycans in cultured retinal pigment epithelium.
PubMed·1987· 38 cited
Glycosaminoglycan synthesis and secretion by bovine retinal capillary pericytes in culture
Experimental Eye Research·1987· 23 cited
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Frequent Co-authors

Geoffrey K. Aguirre(14), Mark E. Haskins(9), Weiye Li(6), John H. Rockey(5), William F. Heath(4), Yuguang Shi(4), Robert J. Desnick(3), Michael R. Jirousek(2), Lawrence M. Ballas(2), Jie An(2), J. Liang(2), John H. Wolfe(2), Edward H. Schuchman(2), Donald F. Patterson(2), Scott Hayes(2), E.L. Pautler(2), Shuyu Shen(2), George A. Robertson(2), Hidehiro Ishii(1), Daisuke Koya(1)