Donald W. MacGlashan

Johns Hopkins University — United States

Immunology and Microbiology · Life Sciences

61h-index11.8kcitations296works0.32yr avg
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Research Topics

Mast cells and histamine(199), Asthma and respiratory diseases(99), Food Allergy and Anaphylaxis Research(91), Coagulation, Bradykinin, Polyphosphates, and Angioedema(70), Urticaria and Related Conditions(53)

Publications292 total

First-In-Human, Proof-of-Mechanism Phase 1 Study of the Oral MRGPRX2 Antagonist SEP-631 Utilizing Short Wave Infrared Imaging to Assess Response to an Icatibant Skin Challenge
Journal of Allergy and Clinical Immunology·2026
The Bruton tyrosine kinase inhibitor acalabrutinib aborts ongoing acute food-induced anaphylactic reactions in humanized mice
Journal of Allergy and Clinical Immunology·2025Open Access
Efficacy of the 4 Subclasses of <scp>IgG</scp> for Interacting With <scp>CD32b/a</scp> on Human Basophils
Clinical & Experimental Allergy·2025Open Access
Immunogenic Profiling of Vancomycin: Detecting Vancomycin-Specific IgG in Patients With and Without Vancomycin Infusion Reactions
Journal of Allergy and Clinical Immunology·2025
Genetic Relationship between SYK Promoter Polymorphism, SYK Expression, and Human Basophils Responses
Journal of Allergy and Clinical Immunology·2025Open Access
The Bruton's Tyrosine Kinase Inhibitor Acalabrutinib Effectively Stops Ongoing IgE-mediated Basophil Activation
Journal of Allergy and Clinical Immunology·2025Open Access
Plasmacytoid Dendritic Cells Display Surface but Not Membrane-Bound IgE Across a Broad Range of Total Serum IgE Levels
EMJ Allergy & Immunology·2025Open Access
Defining Optimal Basophil Passive Sensitisation Parameters
Clinical & Experimental Allergy·2024· 3 citedOpen Access
Examination of IgG Subclasses and CD32b Receptor Expression on Leukocytes Associated with Multi-Allergen Immunotherapy
Journal of Allergy and Clinical Immunology·2024Open Access
Plasmacytoid dendritic cells (pDCs) display surface but not membrane-bound IgE across a broad range of total serum IgE levels
2023· 1 citedOpen Access
MEMBRANE-BOUND IGE EXPRESSION ON PLASMACYTOID DENDRITIC CELLS (PDCS) AND B-CELLS ACROSS TOTAL SERUM IGE LEVELS
Annals of Allergy Asthma & Immunology·2023
A phase II study of Bruton’s tyrosine kinase inhibition for the prevention of anaphylaxis
Journal of Clinical Investigation·2023· 32 citedOpen Access
Bruton’s tyrosine kinase inhibition for the prevention of anaphylaxis: an open-label, phase 2 trial
2023· 2 citedOpen Access
Association of a SYK promoter polymorphism with SYK expression and IgE‐mediated histamine release
Clinical & Experimental Allergy·2023· 4 citedOpen Access
The BTK inhibitor acalabrutinib reduces or eliminates clinical reactivity during oral challenge to peanut in allergic adults
Journal of Allergy and Clinical Immunology·2023· 2 citedOpen Access
Anti-IgE Antibody Therapy
2023· 5 cited
In lasting tribute: Lawrence M. Lichtenstein, May 31, 1934, to August 5, 2022
Journal of Allergy and Clinical Immunology·2022
Biological screening of a unique drug library targeting MRGPRX2
Frontiers in Immunology·2022· 9 citedOpen Access
Subclasses of allergen‐specific IgG: Serum IgG2 and IgG3 levels are not predicted by IgG1/IgG4 levels
Clinical & Experimental Allergy·2021· 6 citedOpen Access
Response of peripheral blood basophils in subjects with chronic spontaneous urticaria during treatment with omalizumab
Journal of Allergy and Clinical Immunology·2021· 33 cited
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Frequent Co-authors

Robert P. Schleimer(15), Lawrence M. Lichtenstein(13), Stephen P. Peters(12), Edward S. Schulman(10), L M Lichtenstein(9), Bruce S. Bochner(9), Sarbjit S. Saini(7), Harold H. Newball(6), L.M. Lichtenstein(6), John T. Schroeder(4), N. Franklin Adkinson(4), Marshall Plaut(4), G. K. Adams(3), Steven Gillis(3), Ann M. Dvořàk(3), David Proud(3), Anne Kagey‐Sobotka(3), Frances M. Davis(3), Bradley J. Undem(2), Edward C. Hayes(2)