Ralf Schmidt

Gladstone Institutes — United States

Medicine · Health Sciences

24h-index2.3kcitations85works21.12yr avg
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Research Topics

CAR-T cell therapy research(15), RNA Research and Splicing(14), T-cell and B-cell Immunology(11), Immune Cell Function and Interaction(11), RNA modifications and cancer(11)

Publications84 total

The Potent and Selective Oral STAT6 Degrader, KT-621, Affects Gene Transcripts in Human Keratinocytes as Effectively as Dupilumab, and Blocks Th2 Inflammation in Atopic Dermatitis and Asthma Mouse Models
SKIN The Journal of Cutaneous Medicine·2025Open Access
The serine/threonine kinase PIM3 acts as essential gatekeeper of T cell functions 2743
The Journal of Immunology·2025Open Access
Integrated epigenetic and genetic programming of primary human T cells
Nature Biotechnology·2025· 9 citedOpen Access
Advanced HyperSight™ imaging for patients with adaptive SBRT of prostate cancer: a longitudinal analysis of tissue demarcation
Radiation Oncology·2025Open Access
T cell receptor associated transmembrane adaptor 1 (TRAT1) modulates human Th17 and Treg responses via PI3-kinase and STAT dependent mechanisms
Cell Communication and Signaling·2025Open Access
Site-specific genome engineering of primary human natural killer cells for programmable anti-tumor function
2025Open Access
Longitudinal stability of HyperSightTM-CBCT based radiomic features in patients with CT guided adaptive SBRT for prostate cancer
Scientific Reports·2025· 2 citedOpen Access
Systematic decoding of cis gene regulation defines context-dependent control of the multi-gene costimulatory receptor locus in human T cells
Nature Genetics·2024· 12 citedOpen Access
MAPP unravels frequent co-regulation of splicing and polyadenylation by RNA-binding proteins and their dysregulation in cancer
Nature Communications·2024· 14 citedOpen Access
Improving prime editing with an endogenous small RNA-binding protein
Nature·2024· 187 citedOpen Access
T helper cells exhibit a dynamic and reversible 3′-UTR landscape
RNA·2024· 5 citedOpen Access
Base-editing mutagenesis maps alleles to tune human T cell functions
Nature·2023· 80 citedOpen Access
Code repository for: Base editing mutagenesis maps functional alleles to tune human T cell activity
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
Code repository for: Base editing mutagenesis maps functional alleles to tune human T cell activity
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
Modular pooled discovery of synthetic knockin sequences to program durable cell therapies
Cell·2023· 61 citedOpen Access
T helper cells exhibit a dynamic and reversible 3’UTR landscape
2023Open Access
Low mortality despite temporary liver dysfunction in severe courses of acute hepatitis E
Wiener klinische Wochenschrift·2022Open Access
A single-cell transcriptional gradient in human cutaneous memory T cells restricts Th17/Tc17 identity
Zenodo (CERN European Organization for Nuclear Research)·2022Open Access
A single-cell transcriptional gradient in human cutaneous memory T cells restricts Th17/Tc17 identity
2022Open Access
A single-cell transcriptional gradient in human cutaneous memory T cells restricts Th17/Tc17 identity
Zenodo (CERN European Organization for Nuclear Research)·2022Open Access
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Frequent Co-authors

Mihaela Zavolan(9), Jan Stange(9), Alexander Marson(8), Klaus G. Schmetterer(8), Andreas Gruber(7), Robert Straßl(7), Florian Mayer(7), Steffen Mitzner(6), Chun Ye(5), Sebastian Klammt(5), Marlene C. Gerner(5), Winfried F. Pickl(5), David Bauer(5), Thomas Reiberger(5), Mattias Mandorfer(5), Georges Martín(4), Souvik Ghosh(4), Justin Eyquem(4), P Peszynski(4), Doris Trapin(4)