Justin Eyquem

Gladstone Institutes — United States

Medicine · Health Sciences

25h-index7.3kcitations93works2.42yr avg
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Research Topics

CAR-T cell therapy research(77), CRISPR and Genetic Engineering(33), Immune Cell Function and Interaction(22), Virus-based gene therapy research(14), Nanowire Synthesis and Applications(13)

Publications92 total

Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells
2025· 2 citedOpen Access
T cell engagers control solid tumors through clonal replacement and IL2-driven effector differentiation of CD8 T cells
2025Open Access
Preclinical development of an optimized manufacturing, CRISPR-edited, fully non-viral 1XX-enhanced anti-BCMA CAR-T therapy for multiple myeloma
Blood·2025Open Access
Machine learning-guided optimization of anti-CD70 natural ligand-based CAR-lymphocytes for Acute Myeloid Leukemia
Blood·2025
778 CRISPR screens reveal innate immune checkpoints regulating NK cell sensitivity across solid tumors
Regular and Young Investigator Award Abstracts·2025Open Access
Investigating functional responses of unique CD16 Fc receptor complexes in human natural killer cells 3218
The Journal of Immunology·2025Open Access
247 UCCT-BCMA-1: a first-in-human, non-viral CRISPR-engineered CAR T cell therapy targeting BCMA in relapsed/refractory multiple myeloma
Regular and Young Investigator Award Abstracts·2025Open Access
Integrated epigenetic and genetic programming of primary human T cells
Nature Biotechnology·2025· 9 citedOpen Access
Decoding Peripheral Tolerance: TCR Rules for pTreg differentiation in the Gut
2025· 2 citedOpen Access
Site-specific genome engineering of primary human natural killer cells for programmable anti-tumor function
2025Open Access
Base-editing a single missense mutation in A20 enhances CAR-T cell efficacy
2025Open Access
In vivo genome-wide CRISPR screens in human T cells to enhance T cell therapy for solid tumors
2025· 1 citedOpen Access
Bicistronic CAR T-cells Against CD70 & Active Integrin β2 Overcome Antigen Heterogeneity and Preserve Safety in Acute Myeloid Leukemia
2025Open Access
Programmable microparticles rewire CAR signaling to enable super-physiological expansion of human T cells <i>in vitro</i>
2025Open Access
T cell receptor precision editing of regulatory T cells for celiac disease
Science Translational Medicine·2025· 5 cited
Peptide-enabled ribonucleoprotein delivery for CRISPR engineering (PERC) in primary human immune cells and hematopoietic stem cells
Nature Protocols·2025· 4 cited
SYK negatively regulates ITAM-mediated human NK cell signaling and CD19-CAR NK cell efficacy
The Journal of Immunology·2025· 4 citedOpen Access
Abstract A020: Induction of non-canonical CAR T cell states in multiple myeloma patients with durable responses
Cancer Immunology Research·2025
Scalable intracellular delivery via microfluidic vortex shedding enhances the function of chimeric antigen receptor T-cells
Scientific Reports·2025· 10 citedOpen Access
SEED-Selection enables high-efficiency enrichment of primary T cells edited at multiple loci
Nature Biotechnology·2025· 12 citedOpen Access
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Frequent Co-authors

Michel Sadelain(16), Alexander Marson(13), Jorge Mansilla‐Soto(10), Mohamad Hamieh(10), Chun Ye(9), Vincent Allain(9), Alexis Talbot(8), Theodore L. Roth(8), William A. Nyberg(8), Brian R. Shy(7), Zhongmei Li(7), Joseph J. Muldoon(7), Judith Feucht(6), Yan Yi Chen(6), Ansuman T. Satpathy(6), Sjoukje J. C. van der Stegen(5), Isabelle Rivière(5), Vivasvan S. Vykunta(5), David N. Nguyen(5), Franziska Blaeschke(5)