Ruby Cai

Gilead Sciences (United States) — United States

Medicine · Health Sciences

10h-index542citations12works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

HIV/AIDS drug development and treatment(8), HIV Research and Treatment(4), Hepatitis C virus research(3), Hepatitis B Virus Studies(2), Monoclonal and Polyclonal Antibodies Research(2)

Publications12 total

GS-9822, a Preclinical LEDGIN Candidate, Displays a Block-and-Lock Phenotype in Cell Culture
Antimicrobial Agents and Chemotherapy·2021· 31 citedOpen Access
Discovery of a Potent and Orally Bioavailable Cyclophilin Inhibitor Derived from the Sanglifehrin Macrocycle
Journal of Medicinal Chemistry·2018· 75 citedOpen Access
Highly Potent HCV NS4B Inhibitors with Activity against Multiple Genotypes
Journal of Medicinal Chemistry·2014· 27 cited
Discovery of GS-9451: An acid inhibitor of the hepatitis C virus NS3/4A protease
Bioorganic & Medicinal Chemistry Letters·2012· 42 citedOpen Access
Discovery of GS-9256: A novel phosphinic acid derived inhibitor of the hepatitis C virus NS3/4A protease with potent clinical activity
Bioorganic & Medicinal Chemistry Letters·2011· 48 cited
Tricyclic HIV integrase inhibitors: Potent and orally bioavailable C5-aza analogs
Bioorganic & Medicinal Chemistry Letters·2008· 23 cited
Design, Synthesis, and SAR Studies of Novel and Highly Active Tri‐Cyclic HIV Integrase Inhibitors.
ChemInform·2006
Effect of Substitution on Novel Tricyclic HIV‐1 Integrase Inhibitors.
ChemInform·2006
Design, synthesis, and SAR studies of novel and highly active tri-cyclic HIV integrase inhibitors
Bioorganic & Medicinal Chemistry Letters·2006· 40 citedOpen Access
Effect of substitution on novel tricyclic HIV-1 integrase inhibitors
Bioorganic & Medicinal Chemistry Letters·2006· 38 citedOpen Access
Small Molecules VP-14637 and JNJ-2408068 Inhibit Respiratory Syncytial Virus Fusion by Similar Mechanisms
Antimicrobial Agents and Chemotherapy·2005· 99 citedOpen Access
Inhibition of Respiratory Syncytial Virus Fusion by the Small Molecule VP-14637 via Specific Interactions with F Protein
Journal of Virology·2003· 119 citedOpen Access

Frequent Co-authors

Haolun Jin(7), Choung U. Kim(7), Michael Mish(5), Salman Jabri(5), Manuel Tsiang(5), Mingzhe Ji(4), Xiaowu Chen(4), Maria Fardis(4), William E. Delaney(3), Hyung‐Jung Pyun(3), Qiaoyin Wu(3), Janet L. Douglas(2), Marites L. Panis(2), Edmund Ho(2), Kuei‐Ying Lin(2), Steve H. Krawczyk(2), Deborah M. Grant(2), S. Swaminathan(2), Tomáš Cihlář(2), Xiaowu Chen(2)