Megan M. King

AstraZeneca (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

4h-index77citations5works0.02yr avg
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Research Topics

Receptor Mechanisms and Signaling(4), Neuroscience and Neuropharmacology Research(3), Pharmacological Receptor Mechanisms and Effects(3), Neuropeptides and Animal Physiology(2), Multicomponent Synthesis of Heterocycles(1)

Publications5 total

In vitro binding of a radio‐labeled positive allosteric modulator for metabotropic glutamate receptor subtype 5
Synapse·2012· 1 cited
4-Piperidin-4-ylidenemethyl-benzamides as δ-opioid receptor agonists for CNS indications: Identifying clinical candidates
Bioorganic & Medicinal Chemistry Letters·2011· 10 citedOpen Access
Multiparameter exploration of piperazine derivatives as δ-opioid receptor agonists for CNS indications
Bioorganic & Medicinal Chemistry Letters·2011· 6 citedOpen Access
Discovery of novel positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5)
Bioorganic & Medicinal Chemistry Letters·2011· 33 citedOpen Access
4-Aryl piperazine and piperidine amides as novel mGluR5 positive allosteric modulators
Bioorganic & Medicinal Chemistry Letters·2010· 27 citedOpen Access

Frequent Co-authors

Valerie Hoesch(5), Nathan Spear(4), Xia Wang(3), R.A. Gadient(3), Kelly Brush(3), John P. McCauley(3), Linda A. Sygowski(2), Dean G. Brown(2), Becky Brockel(2), Vijay Chhajlani(2), Cathy L. Dantzman(2), Glen Ernst(2), Donald W. Andisik(2), Khanh Bui(2), William E. Frietze(2), William E. Palmer(2), Thomas J. Hudzik(2), Steven S. Wesolowski(2), Jeffrey Varnes(1), Andrew P. Marcus(1)