Céline DerMardirossian

San Diego Biomedical Research Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

21h-index2.9kcitations34works2.02yr avg
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Research Topics

Protein Kinase Regulation and GTPase Signaling(13), Cellular Mechanics and Interactions(12), Microtubule and mitosis dynamics(10), Cellular transport and secretion(8), Cell Adhesion Molecules Research(5)

Publications34 total

The Role of Calcium in Actin-Dependent Cell Migration and Invasion in Cancer
Physiology·2024· 2 citedOpen Access
Mechanistic of Rac and Cdc42 synchronization at the cell edge by ARHGAP39-dependent signaling nodules and the impact on protrusion dynamics
2021· 1 citedOpen Access
Mechanism of Rac and Cdc42 Synchronization at the Cell Edge by ARHGAP39-Dependent Signaling and the Impact on Protrusion Dynamics
SSRN Electronic Journal·2021Open Access
Caveolin-1 Phosphorylation Is Essential for Axonal Growth of Human Neurons Derived From iPSCs
Frontiers in Cellular Neuroscience·2019· 21 citedOpen Access
Inhibition of RhoA reduces propofol-mediated growth cone collapse, axonal transport impairment, loss of synaptic connectivity, and behavioural deficits
British Journal of Anaesthesia·2018· 43 citedOpen Access
Engineering Pak1 Allosteric Switches
ACS Synthetic Biology·2017· 35 citedOpen Access
FRET binding antenna reports spatiotemporal dynamics of GDI–Cdc42 GTPase interactions
Nature Chemical Biology·2016· 53 citedOpen Access
Chronophin coordinates cell leading edge dynamics by controlling active cofilin levels
Proceedings of the National Academy of Sciences·2015· 14 citedOpen Access
WISp39 binds phosphorylated Coronin 1B to regulate Arp2/3 localization and Cofilin-dependent motility
The Journal of Cell Biology·2015· 10 citedOpen Access
Protein Tyrosine Phosphatase-PEST and β8 Integrin Regulate Spatiotemporal Patterns of RhoGDI1 Activation in Migrating Cells
Molecular and Cellular Biology·2015· 42 citedOpen Access
Kinome-wide Functional Analysis Highlights the Role of Cytoskeletal Remodeling in Somatic Cell Reprogramming
Cell stem cell·2014· 66 citedOpen Access
GEF-H1
Small GTPases·2013· 25 citedOpen Access
A novel Rac1 GAP splice variant relays poly-Ub accumulation signals to mediate Rac1 inactivation
Molecular Biology of the Cell·2012· 19 citedOpen Access
Reactive Oxygen Species Regulate Protrusion Efficiency by Controlling Actin Dynamics
PLoS ONE·2012· 62 citedOpen Access
The Microtubule-Associated Rho Activating Factor GEF-H1 Interacts with Exocyst Complex to Regulate Vesicle Traffic
Developmental Cell·2012· 67 citedOpen Access
Pak1 regulates focal adhesion strength, myosin IIA distribution, and actin dynamics to optimize cell migration
The Journal of Cell Biology·2011· 90 citedOpen Access
c-Src–Mediated Phosphorylation of NoxA1 and Tks4 Induces the Reactive Oxygen Species (ROS)–Dependent Formation of Functional Invadopodia in Human Colon Cancer Cells
Molecular Biology of the Cell·2010· 108 citedOpen Access
A Novel and Specific NADPH Oxidase-1 (Nox1) Small-Molecule Inhibitor Blocks the Formation of Functional Invadopodia in Human Colon Cancer Cells
ACS Chemical Biology·2010· 185 cited
Direct interaction between Tks proteins and the N-terminal proline-rich region (PRR) of NoxA1 mediates Nox1-dependent ROS generation
European Journal of Cell Biology·2010· 55 cited
Chronophin and Slingshot Cofilin Phosphatases in Cytoskeletal Regulation
Elsevier eBooks·2010
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Frequent Co-authors

Gary Bokoch(20), Violaine Delorme-Walker(8), Ritu Pathak(4), Michael Howell(4), Klaus M. Hahn(4), Timothy Y. Huang(3), Gaudenz Danuser(3), Davide Gianni(3), Nicolas Taulet(3), Anthony Anselmo(3), Karen Anderson(2), Dorit Hanein(2), Clare M. Waterman(2), Onur Dağliyan(2), Hemal H. Patel(2), Piyush M. Patel(2), Brian P. Head(2), Andreas Schnelzer(1), Violaine Delorme(1), Matthias Macháček(1)