Davide Gianni

Biogen (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

30h-index3.9kcitations103works3.92yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Virus-based gene therapy research(24), Herpesvirus Infections and Treatments(15), Animal Virus Infections Studies(14), CRISPR and Genetic Engineering(10), Alzheimer's disease research and treatments(9)

Publications103 total

Inhibition of immune response reduces pathology in dorsal root ganglia and peripheral nerves in cynomolgus macaques following AAV gene therapy
Molecular Therapy — Methods & Clinical Development·2025· 1 citedOpen Access
The limitations of small molecule and genetic screening in phenotypic drug discovery
Cell chemical biology·2025· 1 cited
Detecting MUNC18-1 related presynaptic dysfunction and rescue in human iPSC-derived neurons
Scientific Reports·2025Open Access
146 (PB134): First disclosure of AZD3470, a highly potent MTA-cooperative PRMT5 inhibitor in PRIMROSE and PRIMAVERA clinical studies
European Journal of Cancer·2024· 1 cited
422 (PB410): Understanding Mechanisms of Cancer Drug Sensitivity and Resistance Using Functional Genomic Approaches
European Journal of Cancer·2024
Discovery and <i>In Vivo</i> Efficacy of AZ-PRMT5i-1, a Novel PRMT5 Inhibitor with High MTA Cooperativity
Journal of Medicinal Chemistry·2024· 18 citedOpen Access
Adeno-Associated Virus-Mediated Dorsal Root Ganglion Toxicity in the New Zealand White Rabbit
Toxicologic Pathology·2024· 6 cited
Identification of negative regulators of Wnt/β-catenin signaling in lung epithelial cells through whole genome CRISPR screen
2023
CRISPR screening in primary human lung fibroblasts and small airway epithelial cells identifies novel targets to reduce cellular senescence with potential to treat both COPD and IPF
2023
Abstract 3088: Identification of a novel series of MTAP-selective PRMT5 inhibitors, and first disclosure of AZ-PRMT5i-1
Cancer Research·2023· 3 cited
Supplementary Figure 1B from Depletion of Peripheral Macrophages and Brain Microglia Increases Brain Tumor Titers of Oncolytic Viruses
2023Open Access
Supplementary Figure 2 from Depletion of Peripheral Macrophages and Brain Microglia Increases Brain Tumor Titers of Oncolytic Viruses
2023Open Access
Data from Depletion of Peripheral Macrophages and Brain Microglia Increases Brain Tumor Titers of Oncolytic Viruses
2023Open Access
Supplementary Figure 1A from Depletion of Peripheral Macrophages and Brain Microglia Increases Brain Tumor Titers of Oncolytic Viruses
2023Open Access
Supplementary Figure 1A from Depletion of Peripheral Macrophages and Brain Microglia Increases Brain Tumor Titers of Oncolytic Viruses
2023Open Access
Data from Depletion of Peripheral Macrophages and Brain Microglia Increases Brain Tumor Titers of Oncolytic Viruses
2023Open Access
Supplementary Figure 4 from Depletion of Peripheral Macrophages and Brain Microglia Increases Brain Tumor Titers of Oncolytic Viruses
2023Open Access
Supplementary Figure 3 from Depletion of Peripheral Macrophages and Brain Microglia Increases Brain Tumor Titers of Oncolytic Viruses
2023Open Access
Supplementary Figure 5 from Depletion of Peripheral Macrophages and Brain Microglia Increases Brain Tumor Titers of Oncolytic Viruses
2023Open Access
Supplementary Figure 1B from Depletion of Peripheral Macrophages and Brain Microglia Increases Brain Tumor Titers of Oncolytic Viruses
2023Open Access
page 1 of 6Next →

Frequent Co-authors

Miguel Sena‐Esteves(7), Gary Bokoch(7), Federica del Monte(5), Nicola Zambrano(5), Tommaso Russo(5), Giulia Fulci(4), E. Antonio Chiocca(4), Balveen Kaur(3), Ralph Weissleder(3), Xandra O. Breakefield(3), Nicolas Taulet(3), Céline DerMardirossian(3), Marc J. Semigran(3), Marida Bimonte(3), Norbert Schweifer(2), Ulrike Tontsch-Grunt(2), Norbert Kraut(2), Casey A. Maguire(2), Jérémy Kister(2), Luis E. Martínez(2)