Cynthia A. Leifer

Cornell University — United States

Immunology and Microbiology · Life Sciences

34h-index6.0kcitations67works1.02yr avg
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Research Topics

Immune Response and Inflammation(32), Immunotherapy and Immune Responses(17), Immune Cell Function and Interaction(12), Antimicrobial Peptides and Activities(12), Gut microbiota and health(5)

Publications67 total

Commensal taxa in gut microbiota limit antibiotic resistance during extended oral antibiotic use
2025Open Access
Gut commensal microbiota drive tailored macrophage responses
Cell Reports·2025· 2 citedOpen Access
Generation of primary feline chimeric antigen receptor T cells
American Journal of Veterinary Research·2024Open Access
Regulation of TAR DNA binding protein 43 (TDP-43) homeostasis by cytosolic DNA accumulation
Journal of Biological Chemistry·2024· 2 citedOpen Access
A Role for Stimulator of Interferon Genes in Toll-Like Receptor 8 Signaling
The Journal of Immunology·2023Open Access
Racing CARs to veterinary immuno-oncology
Frontiers in Veterinary Science·2023· 3 citedOpen Access
Macrophage uptake of oxidized and acetylated low-density lipoproteins and generation of reactive oxygen species are regulated by linear stiffness of the growth surface
PLoS ONE·2021· 19 citedOpen Access
Molecular regulation of TLR signaling in health and disease: mechano-regulation of macrophages and TLR signaling
Innate Immunity·2020· 42 citedOpen Access
Immunomodulatory nanogels overcome restricted immunity in a murine model of gut microbiome–mediated metabolic syndrome
Science Advances·2019· 36 citedOpen Access
Gut microbiota influence B cell function in a TLR5-dependent manner
2019· 1 citedOpen Access
Mitochondrial DNA in the tumour microenvironment activates neutrophils and is associated with worse outcomes in patients with advanced epithelial ovarian cancer
British Journal of Cancer·2018· 95 citedOpen Access
HHV-6B infection, T-cell reconstitution, and graft-vs-host disease after hematopoietic stem cell transplantation
Bone Marrow Transplantation·2018· 24 citedOpen Access
Toll-like receptor signaling in macrophages is regulated by extracellular substrate stiffness and Rho-associated coiled-coil kinase (ROCK1/2)
International Immunology·2018· 65 citedOpen Access
The decidua of preeclamptic-like BPH/5 mice exhibits an exaggerated inflammatory response during early pregnancy
Journal of Reproductive Immunology·2017· 30 cited
The effect of cell debris within biologic scaffolds upon the macrophage response
Journal of Biomedical Materials Research Part A·2017· 72 cited
Safe Recombinant Outer Membrane Vesicles that Display M2e Elicit Heterologous Influenza Protection
Molecular Therapy·2017· 102 citedOpen Access
Dendritic cells in host response to biologic scaffolds
Seminars in Immunology·2017· 32 cited
Complex Negative Regulation of TLR9 by Multiple Proteolytic Cleavage Events
The Journal of Immunology·2016· 18 citedOpen Access
Molecular mechanisms of regulation of Toll-like receptor signaling
Journal of Leukocyte Biology·2016· 238 citedOpen Access
Macrophage lipid accumulation is regulated by substrate stiffness
The Journal of Immunology·2016· 3 cited
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Frequent Co-authors

David M. Segal(9), Alessandra Mazzoni(7), James C. Brooks(6), Jody Cameron(6), Margaret Kennedy(5), Annapoorani Chockalingam(5), William Rose(5), Erika J. Gruber(5), Gregory Mullen(4), Dennis M. Klinman(4), Kaori Sakamoto(3), Matthew P. DeLisa(3), David Putnam(3), Maroof Hasan(3), David R. Davies(2), Alan Sher(2), Fumihiko Takeshita(2), İhsan Gürsel(2), Ken J. Ishii(2), Mayda Gürsel(2)