William Rose

Merck & Co., Inc., Rahway, NJ, USA (United States) — United States

Immunology and Microbiology · Life Sciences

14h-index767citations26works4.02yr avg
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Research Topics

Immune Response and Inflammation(9), Immune Cell Function and Interaction(8), Immunotherapy and Immune Responses(6), Herpesvirus Infections and Treatments(4), IL-33, ST2, and ILC Pathways(3)

Publications26 total

Evaluation of a non-nucleoside inhibitor of the RSV RNA-dependent RNA polymerase in translatable animals models
Journal of Infection·2024· 5 citedOpen Access
Discovery of Broad-Spectrum Herpes Antiviral Oxazolidinone Amide Derivatives and Their Structure–Activity Relationships
ACS Medicinal Chemistry Letters·2024· 3 citedOpen Access
A novel rotavirus reverse genetics platform supports flexible insertion of exogenous genes and enables rapid development of a high-throughput neutralization assay
2023· 3 citedOpen Access
Interleukin-33 Contributes Toward Loss of Tolerance by Promoting B-Cell-Activating Factor of the Tumor-Necrosis-Factor Family (BAFF)-Dependent Autoantibody Production
Frontiers in Immunology·2018· 21 citedOpen Access
IL-33 released by alum is responsible for early cytokine production and has adjuvant properties
Scientific Reports·2015· 47 citedOpen Access
IL-33 drives alum-induced cytokine production and provides a robust secondary antibody response independently of alum (CCR4P.211)
The Journal of Immunology·2015
TRADITIONAL BIOCHEMICAL ASSAYS FOR STUDYING TOLL-LIKE RECEPTOR 9
Journal of Immunoassay and Immunochemistry·2013· 3 citedOpen Access
TLR9 is important for protection against intestinal damage and for intestinal repair
Scientific Reports·2012· 83 citedOpen Access
Multifunctional role of dextran sulfate sodium for in vivo modeling of intestinal diseases
BMC Immunology·2012· 56 citedOpen Access
Heterozygous Carriage of a Dysfunctional Toll-like Receptor 9 Allele Affects CpG Oligonucleotide Responses in B Cells
Journal of Biological Chemistry·2012· 7 citedOpen Access
Correction: Cutting Edge: A TLR9 Cytoplasmic Tyrosine Motif Is Selectively Required for Proinflammatory Cytokine Production
The Journal of Immunology·2012Open Access
Commensal Bacteria Modulate Innate Immune Responses of Vaginal Epithelial Cell Multilayer Cultures
PLoS ONE·2012· 142 citedOpen Access
Cutting Edge: A TLR9 Cytoplasmic Tyrosine Motif Is Selectively Required for Proinflammatory Cytokine Production
The Journal of Immunology·2011· 25 citedOpen Access
FSL-1, a bacterial-derived toll-like receptor 2/6 agonist, enhances resistance to experimental HSV-2 infection
Virology Journal·2009· 26 citedOpen Access
Evaluation of immunomodulatory compounds for identification of an anti-herpetic innate immune response profile
2009
Heterogeneous Interleukin-15 Inducibilities in Murine B16 Melanoma and RM-1 Prostate Carcinoma by Interferon-α Treatment
Journal of Interferon & Cytokine Research·2009· 1 citedOpen Access
An immunomodulating dipeptide, SCV-07, is a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2)
International Journal of Antimicrobial Agents·2008· 19 cited
ORIGINAL ARTICLE: Quantification and Comparison of Toll‐Like Receptor Expression and Responsiveness in Primary and Immortalized Human Female Lower Genital Tract Epithelia
American Journal of Reproductive Immunology·2008· 136 cited
IFN-α-Induced Murine B16 Melanoma Cancer Vaccine Cells: Induction and Accumulation of Cell-Associated IL-15
Journal of Interferon & Cytokine Research·2007· 29 cited
Scanning cytometry with a LEAP: Laser‐enabled analysis and processing of live cells in situ
Cytometry Part A·2006· 25 citedOpen Access
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Frequent Co-authors

Cynthia A. Leifer(6), Richard B. Pyles(4), Angela J. Okragly(3), Robert J. Benschop(3), Lisa M. Reece(3), James F. Leary(3), Chris L. McGowin(2), Rae Ann Spagnuolo(2), Kaori Sakamoto(2), Chetan N. Patel(2), Tzu G. Wu(2), Thomas Albrecht(2), Eugene P. Knutson(2), Joana R. Perdigão(2), W. R. Fleischmann(2), Annapoorani Chockalingam(2), Maroof Hasan(2), Chia‐Hsin Ju(2), Tarl W. Prow(2), Ron W. Darbeau(2)