Neil S. Forbes

Amherst College — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

36h-index6.9kcitations96works3.22yr avg
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Research Topics

Cancer Research and Treatments(49), Nanoplatforms for cancer theranostics(26), Virus-based gene therapy research(24), Bacteriophages and microbial interactions(17), 3D Printing in Biomedical Research(11)

Publications96 total

Recombinant CALR polarizes and activates macrophages in tumors
Molecular Therapy Oncology·2025Open Access
Mathematical Modeling of Salmonella Cancer Therapies Demonstrates the Necessity of Both Bacterial Cytotoxicity and Immune Activation
Bioengineering·2025Open Access
Abstract 480: An engineered bacterial delivery platform, BacID, selectively delivers activated Caspase-3 into the cytoplasm of cancer cells, eliminating tumors and reducing metastatic burden
Cancer Research·2025
Controlling intracellular protein delivery, tumor colonization and tissue distribution using flhDC in clinically relevant ΔsseJ Salmonella
Molecular Therapy·2024· 1 cited
Controlled production of lipopolysaccharides increases immune activation in Salmonella treatments of cancer
Microbial Biotechnology·2024· 7 citedOpen Access
Intracellular delivery of oncolytic viruses with engineered Salmonella causes viral replication and cell death
iScience·2024· 11 citedOpen Access
In vivo evaluation of new adjuvant systems based on combination of Salmonella Typhi porins with particulate systems: Liposomes versus polymeric particles
International Journal of Pharmaceutics·2023· 8 cited
Intracellular Salmonella delivery of an exogenous immunization antigen refocuses CD8 T cells against cancer cells, eliminates pancreatic tumors and forms antitumor immunity
Frontiers in Immunology·2023· 18 citedOpen Access
Build-a-bug workshop: Using microbial-host interactions and synthetic biology tools to create cancer therapies
Cell Host & Microbe·2023· 27 cited
Bacterial delivery of therapeutic proteins to the nuclei of cancer cells
Biotechnology and Bioengineering·2023· 3 citedOpen Access
Microbial Imbalance Induces Inflammation by Promoting <i>Salmonella</i> Penetration through the Mucosal Barrier
ACS Infectious Diseases·2022· 7 cited
Targeting circulating monocytes with CCL2-loaded liposomes armed with an oncolytic adenovirus
Nanomedicine Nanotechnology Biology and Medicine·2021· 26 cited
Intracellular delivery of protein drugs with an autonomously lysing bacterial system reduces tumor growth and metastases
Nature Communications·2021· 150 citedOpen Access
Bacteria-based immune therapies for cancer treatment
Seminars in Cancer Biology·2021· 41 cited
<i>Escherichia coli</i> Swimming back Toward Stiffer Polyetheylene Glycol Coatings, Increasing Contact in Flow
ACS Applied Materials & Interfaces·2021· 8 citedOpen Access
Source Data
Figshare·2021· 1 citedOpen Access
Source Data
Figshare·2021Open Access
Microfluidic platforms to study host-microbiome interactions
2020Open Access
Mucus blocks probiotics but increases penetration of motile pathogens and induces TNF‐α and IL‐8 secretion
Biotechnology and Bioengineering·2020· 7 citedOpen Access
Abstract IA24: Engineered <i>Salmonella</i> for drug delivery to solid tumors
Cancer Research·2020
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Frequent Co-authors

Nele Van Dessel(8), Byoung‐Jin Kim(6), Yvonne Perrie(6), Charles A. Swofford(6), Gang Han(5), Vincent M. Rotello(5), Jan T. Panteli(5), Bhushan J. Toley(4), Rachel W. Kasinskas(4), Vishnu Raman(4), Rakesh K. Jain(3), Maryam T. Hussain(3), Raja Venkatasubramanian(3), Adam St. Jean(3), Miaomin Zhang(3), Lars M. Howell(3), Chaekyu Kim(2), Chang‐Cheng You(2), Rosemary S. Turingan(2), Craig T. Martin(2)