Hartmut Wekerle

Max Planck Institute for Intelligent Systems — Germany

Immunology and Microbiology · Life Sciences

98h-index33.1kcitations468works7.82yr avg
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Research Topics

T-cell and B-cell Immunology(139), Immunotherapy and Immune Responses(107), Neuroinflammation and Neurodegeneration Mechanisms(84), Monoclonal and Polyclonal Antibodies Research(71), Multiple Sclerosis Research Studies(68)

Publications467 total

Multiple sclerosis and gut microbiota: Lachnospiraceae from the ileum of MS twins trigger MS-like disease in germfree transgenic mice—An unbiased functional study
Proceedings of the National Academy of Sciences·2025· 18 citedOpen Access
Fragments of the brain’s myelin proteins train T cells to ward off autoimmune attacks
Nature·2024
Life history of a brain autoreactive T cell: From thymus through intestine to blood-brain barrier and brain lesion
Neurotherapeutics·2024· 7 citedOpen Access
Multiple sclerosis and the intestine: Chasing the microbial offender
Immunological Reviews·2024· 6 citedOpen Access
A B cell–driven EAE mouse model reveals the impact of B cell–derived cytokines on CNS autoimmunity
Proceedings of the National Academy of Sciences·2023· 13 citedOpen Access
Visualizing the activation of encephalitogenic T cells in the ileal lamina propria by in vivo two-photon imaging
Proceedings of the National Academy of Sciences·2023· 13 citedOpen Access
Review for "Neuroanatomy of lymphoid organs: Lessons learned from whole‐tissue imaging studies"
2023
Review for "Neuroanatomy of lymphoid organs: Lessons learned from whole‐tissue imaging studies"
2023
Correction: Broader Epstein–Barr virus–specific T cell receptor repertoire in patients with multiple sclerosis
The Journal of Experimental Medicine·2022· 1 citedOpen Access
Broader Epstein–Barr virus–specific T cell receptor repertoire in patients with multiple sclerosis
The Journal of Experimental Medicine·2022· 83 citedOpen Access
Gut microbiome of multiple sclerosis patients and paired household healthy controls reveal associations with disease risk and course
Cell·2022· 279 citedOpen Access
Epstein–Barr virus sparks brain autoimmunity in multiple sclerosis
Nature·2022· 18 cited
Cumulative Autoimmunity: T Cell Clones Recognizing Several Self-Epitopes Exhibit Enhanced Pathogenicity
UNC Libraries·2020Open Access
Exploring the gut microbiome in multiple sclerosis via the international MS Microbiome Study (iMSMS)
MPG.PuRe (Max Planck Society)·2020Open Access
Intestinal microbiota and neurological disease
Journal of the Neurological Sciences·2019· 1 cited
Autoimmune diabetes mellitus and the leaky gut
Proceedings of the National Academy of Sciences·2019· 15 citedOpen Access
Avraham Ben‐Nun—Pioneer, fighter, friend
European Journal of Immunology·2019· 1 citedOpen Access
The Genetic Background of Mice Influences the Effects of Cigarette Smoke on Onset and Severity of Experimental Autoimmune Encephalomyelitis
International Journal of Molecular Sciences·2019· 6 citedOpen Access
Secondary progressive multiple sclerosis and the gut-brain axis
Brain·2019· 4 citedOpen Access
Brain inflammatory cascade controlled by gut-derived molecules
Nature·2018· 20 cited
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Frequent Co-authors

Reinhard Hohlfeld(16), Hans Lassmann(15), Harald Neumann(7), Christopher Linington(6), Dieter E. Jenne(6), Gurumoorthy Krishnamoorthy(5), Markus Krumbholz(5), Edgar Meinl(5), Alexander Flügel(4), Kerstin Berer(3), Martin Kerschensteiner(3), Wolfgang E. F. Klinkert(3), Christine Stadelmann(3), Tania Kümpfel(3), Francesca Odoardi(3), Joachim W. Ellwart(3), Tobias Derfuß(3), Klaus Dornmair(3), Marsilius Mues(2), Thomas Misgeld(2)