Sajjan Koirala

Amgen (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

6h-index383citations14works2.52yr avg
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Research Topics

Protein Degradation and Inhibitors(5), Cellular transport and secretion(4), Ubiquitin and proteasome pathways(4), Mitochondrial Function and Pathology(3), Parathyroid Disorders and Treatments(3)

Publications14 total

LYMTACs:chimeric small molecules repurpose lysosomal membrane proteins for target protein relocalization and degradation
Nature Communications·2025· 4 citedOpen Access
Covalent Destabilizing Degrader of AR and AR-V7 in Androgen-Independent Prostate Cancer Cells
Journal of the American Chemical Society·2025· 4 cited
Covalent Destabilizing Degrader of AR and AR-V7 in Androgen-Independent Prostate Cancer Cells
2025· 2 citedOpen Access
LYMTACs: Chimeric Small Molecules Repurpose Lysosomal Membrane Proteins for Target Protein Relocalization and Degradation
2024Open Access
Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase
Cell Reports·2020· 17 citedOpen Access
Correction: γKlotho is a novel marker and cell survival factor in a subset of triple negative breast cancers
Oncotarget·2019· 1 citedOpen Access
Correction: Klotho is a novel marker and cell survival factor in a subset of triple negative breast cancers (Oncotarget (2016) 7 (2611-2628) DOI: 10.18632/oncotarget.6006)
2019
An Acetyldegron Triggers CRBN to Take Down the “Q”
Molecular Cell·2016· 4 cited
γKlotho is a novel marker and cell survival factor in a subset of triple negative breast cancers
Oncotarget·2015· 13 citedOpen Access
The structural and functional roles of mitochondrial fission adaptors in yeast and humans
J. Willard Marriott Library·2015Open Access
Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission
Proceedings of the National Academy of Sciences·2013· 191 citedOpen Access
The Mitochondrial Fission Adaptors Caf4 and Mdv1 Are Not Functionally Equivalent
PLoS ONE·2012· 28 citedOpen Access
Molecular architecture of a dynamin adaptor: implications for assembly of mitochondrial fission complexes
The Journal of Cell Biology·2010· 43 citedOpen Access
Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain
Nature Structural & Molecular Biology·2006· 76 cited

Frequent Co-authors

Patrick Ryan Potts(9), Klementina Fon Tacer(4), Janet M. Shaw(3), Nuša Trošt(3), Samuel Peña‐Llopis(3), Jurij Stojan(3), Elisabeth D. Martínez(3), Qian Guo(2), Huyen Bui(2), Debra M. Eckert(2), Christopher P. Hill(2), Cory M. Nadel(2), Ying Q. Lin(2), Daniel K. Nomura(2), Dhanusha A. Nalawansha(2), Georgios Mazis(2), Gitte Husemoen(2), Kate S. Ashton(2), Weixian Deng(2), Ryan P. Wurz(2)