Teresa Sullivan

National Institutes of Health — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index4.6kcitations31works14.02yr avg
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Research Topics

CRISPR and Genetic Engineering(12), Nuclear Structure and Function(11), RNA Research and Splicing(10), Genomics and Chromatin Dynamics(7), BRCA gene mutations in cancer(6)

Publications31 total

A single BRCA2 BRC repeat supports viability while multiple repeats ensure resilience under stress
2026Open Access
Saturation genome editing-based clinical classification of BRCA2 variants
Nature·2025· 28 cited
Spatiotemporal modulation of growth factors directs the generation of multilineage mouse embryonic stem cell-derived mammary organoids
Developmental Cell·2023· 13 citedOpen Access
AVENGERS: Analysis of Variant Effects using Next Generation sequencing to Enhance <i>BRCA2</i> Stratification
2023· 2 citedOpen Access
Characterization of BRCA2 R3052Q variant in mice supports its functional impact as a low-risk variant
Cell Death and Disease·2023· 3 citedOpen Access
Protocol for the saturation and multiplexing of genetic variants using CRISPR-Cas9
STAR Protocols·2023· 4 citedOpen Access
Sequencing-based functional assays for classification of BRCA2 variants in mouse ESCs
Cell Reports Methods·2023· 2 citedOpen Access
Saturation genome editing of 11 codons and exon 13 of BRCA2 coupled with chemotherapeutic drug response accurately determines pathogenicity of variants
PLoS Genetics·2023· 16 citedOpen Access
Abrogation of Rb Tumor Suppression Initiates GBM in Differentiated Astrocytes by Driving a Progenitor Cell Program
Frontiers in Oncology·2022· 7 citedOpen Access
Epidemiological and ES cell‐based functional evaluation of <i>BRCA2</i> variants identified in families with breast cancer
Human Mutation·2020· 6 citedOpen Access
A computational model for classification of BRCA2 variants using mouse embryonic stem cell-based functional assays
npj Genomic Medicine·2020· 29 citedOpen Access
Calibration of Pathogenicity Due to Variant-Induced Leaky Splicing Defects by Using <i>BRCA2</i> Exon 3 as a Model System
Cancer Research·2020· 24 citedOpen Access
Functional evaluation of five BRCA2 unclassified variants identified in a Sri Lankan cohort with inherited cancer syndromes using a mouse embryonic stem cell-based assay
Breast Cancer Research·2020· 7 citedOpen Access
The Educationalization of Student Emotional and Behavioral Health
2018· 9 cited
Dynamic silencing of somatic L1 retrotransposon insertions reflects the developmental and cellular contexts of their genomic integration
Mobile DNA·2017· 15 citedOpen Access
RB inactivation in keratin 18 positive thymic epithelial cells promotes non-cell autonomous T cell hyperproliferation in genetically engineered mice
PLoS ONE·2017· 2 citedOpen Access
Synthetic viability by BRCA2 and PARP1/ARTD1 deficiencies
Nature Communications·2016· 138 citedOpen Access
Abstract 2626: Characterization of the invading cells in glioblastoma using a syngeneic intracranial transplant tumor model.
Cancer Research·2013
Abstract 5014: Reprogramming of mature astrocytes by abrogation of Rb tumor suppression leads to astrocytoma initiation in GEMMs.
Cancer Research·2013
Abstract 3346: Astrocytoma initiation by Rb family inactivation induced dedifferentiation of mature astrocytes.
Cancer Research·2012
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Frequent Co-authors

Shyam K. Sharan(13), Colin L. Stewart(11), Eileen Southon(11), Sounak Sahu(8), Kajal Biswas(6), Sandra Burkett(5), Linda Cleveland(5), Stacey Stauffer(5), Terry Van Dyke(5), Susan Reid(4), Dylan Caylor(4), Amit S. Adhikari(4), Josephine Geh(3), Raj Chari(3), Arun Prakash Mishra(3), T. Norene O’Sullivan(3), Mary Albaugh(3), Lucy Lu(3), Yurong Song(3), Brian Burke(2)