Colin L. Stewart

Biochemistry, Genetics and Molecular Biology · Life Sciences

104h-index42.2kcitations288works0.02yr avg
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Research Topics

Nuclear Structure and Function(112), RNA Research and Splicing(89), Genomics and Chromatin Dynamics(51), Reproductive System and Pregnancy(32), Pluripotent Stem Cells Research(29)

Publications288 total

1079 ROS1-Associated Uterine Inflammatory Myofibroblastic Tumours: Rare Neoplasms Occurring Over a Wide Age Range and with Potentially Aggressive Behaviour
Laboratory Investigation·2025
The Role of β-Dystroglycan in Nuclear Dynamics
Cells·2024Open Access
Abstract 12498: AAV-Mediated LINC Complex Uncoupling Ameliorates Pathology in a Mouse Model of <i>LMNA</i> Dilated Cardiomyopathy
Circulation·2023
Tumor-derived interleukin-1α and leukemia inhibitory factor promote extramedullary hematopoiesis
PLoS Biology·2023· 13 citedOpen Access
Abstract 13927: AAV Gene Therapy to Treat Underlying Cardiac Biomechanical Defects in <i>Lmna</i> Dilated Cardiomyopathy Improves Lifespan and Preserves Ejection Fraction in <i>Lmna</i> DCM Mouse Model
Circulation·2022· 2 cited
Synergistic Combined-proteomics Guided Mapping strategy identifies mTOR mediated phosphorylation of LARP1 in nutrient responsiveness and dilated cardiomyopathy
2022· 1 citedOpen Access
Nesprin-1 LINC complexes recruit microtubule cytoskeleton proteins and drive pathology in<i>Lmna</i>-mutant striated muscle
Human Molecular Genetics·2022· 35 citedOpen Access
Characterizing arrhythmia using machine learning analysis of Ca2+ cycling in human cardiomyocytes
Stem Cell Reports·2022· 42 citedOpen Access
Interleukin-1α and Leukemia Inhibitory Factor Promote Extramedullary Hematopoiesis
2022Open Access
RTL1/PEG11 imprinted in human and mouse brain mediates anxiety-like and social behaviors and regulates neuronal excitability in the locus coeruleus
Human Molecular Genetics·2022· 35 citedOpen Access
Upregulation of the JAK-STAT pathway promotes maturation of human embryonic stem cell-derived cardiomyocytes
Stem Cell Reports·2021· 6 citedOpen Access
AKTIP interacts with ESCRT I and is needed for the recruitment of ESCRT III subunits to the midbody
PLoS Genetics·2021· 20 citedOpen Access
Disrupting the LINC complex by AAV mediated gene transduction prevents progression of Lamin induced cardiomyopathy
Nature Communications·2021· 87 citedOpen Access
The lipid phosphatase LPP3 regulates extra-embryonic vasculogenesis and axis patterning
UNC Libraries·2021Open Access
Combination of haploinsufficiency and dominant negative effects of mutant lamin A/C are responsible for the increased severity of L-CMD compared with EDMD
HAL (Le Centre pour la Communication Scientifique Directe)·2021
LINC complex regulation of genome organization and function
Current Opinion in Genetics & Development·2021· 38 cited
Lamin A/C–mediated neuromuscular junction defects in Emery-Dreifuss muscular dystrophy
UNC Libraries·2020Open Access
The Laminopathies and the Insights They Provide into the Structural and Functional Organization of the Nucleus
Annual Review of Genomics and Human Genetics·2020· 57 cited
Lamin A/C Assembly Defects in LMNA-Congenital Muscular Dystrophy Is Responsible for the Increased Severity of the Disease Compared with Emery–Dreifuss Muscular Dystrophy
Cells·2020· 44 citedOpen Access
Heterochromatin loss as a determinant of progerin‐induced DNA damage in Hutchinson–Gilford Progeria
Aging Cell·2020· 52 citedOpen Access
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Frequent Co-authors

Brian Burke(6), Harshida Bhatt(5), Teresa Sullivan(5), Frank Köntgen(4), Jan Lammerding(4), Serguei Kozlov(4), Richard Lee(4), Susan J. Abbondanzo(3), P. Christian Schulze(3), С. В. Козлов(3), Lisa J. Brunet(2), Inder Gadi(2), Annachiara De Sandre‐Giovannoli(2), Nicolas Lévy(2), Diana Escalante‐Alcalde(2), Tomosaburo Takahashi(2), Roger D. Kamm(2), Jack Silver(2), Shyam B. Khatau(2), Christopher M. Hale(2)