Theodore P. Rasmussen

University of Connecticut — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

47h-index9.9kcitations126works12.72yr avg
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Research Topics

Pluripotent Stem Cells Research(27), Epigenetics and DNA Methylation(19), Epilepsy research and treatment(15), Genomics and Chromatin Dynamics(14), CRISPR and Genetic Engineering(14)

Publications126 total

Correlations of Long Noncoding RNA HNF4A-AS1 Alternative Transcripts with Liver Diseases and Drug Metabolism
Drug Metabolism and Disposition·2024· 3 citedOpen Access
Mechanisms of Action of the US Food and Drug Administration-Approved Antisense Oligonucleotide Drugs
BioDrugs·2024· 30 citedOpen Access
Identification and Functional Characterization of Alternative Transcripts of LncRNA HNF1A-AS1 and Their Impacts on Cell Growth, Differentiation, Liver Diseases, and in Response to Drug Induction
Non-Coding RNA·2024· 5 citedOpen Access
Targeting the Liver with Nucleic Acid Therapeutics for the Treatment of Systemic Diseases of Liver Origin
Pharmacological Reviews·2023· 19 citedOpen Access
Nephrotoxicity of marketed antisense oligonucleotide drugs
Current Opinion in Toxicology·2022· 26 citedOpen Access
Nedosiran, a Candidate siRNA Drug for the Treatment of Primary Hyperoxaluria: Design, Development, and Clinical Studies
ACS Pharmacology & Translational Science·2022· 43 citedOpen Access
Belzutifan (Welireg™) for von Hippel Lindau disease
Trends in Pharmacological Sciences·2022· 3 cited
Absorption, Distribution, Metabolism, and Excretion of FDA‐approved Antisense Oligonucleotide Drugs
The FASEB Journal·2022· 2 cited
Modeling the kidney with human pluripotent cells: Applications for toxicology and organ repair
Current Opinion in Toxicology·2022· 1 cited
Absorption, Distribution, Metabolism, and Excretion of US Food and Drug Administration–Approved Antisense Oligonucleotide Drugs
Drug Metabolism and Disposition·2022· 99 citedOpen Access
Adverse Drug Reactions and Toxicity of the Food and Drug Administration–Approved Antisense Oligonucleotide Drugs
Drug Metabolism and Disposition·2022· 106 citedOpen Access
Efficient and Rapid generation of anti-aging neural stem cells by direct conversion Fibroblasts with A Single microRNA
2021Open Access
<i>Epigenetics, Nuclear Organization and Gene Function: With Implications of Epigenetic Regulation and Genetic Architecture for Human Development and Health</i>. By John C. Lucchesi. Oxford and New York: Oxford University Press. $100.00 (hardcover); $49.95 (paper). xviii + 286 p.; ill.; index. ISBN: 978-0-19-883120-4 (hc); 978-0-19-883121-1 (pb). 2019.
The Quarterly Review of Biology·2021
The growth of siRNA-based therapeutics: Updated clinical studies
Biochemical Pharmacology·2021· 465 citedOpen Access
lnc‐RHL, a novel long non‐coding RNA required for the differentiation of hepatocytes from human bipotent progenitor cells
Cell Proliferation·2021· 11 citedOpen Access
lncRNA involvement in cancer stem cell function and epithelial-mesenchymal transitions
Seminars in Cancer Biology·2020· 332 cited
Emerging Therapeutic Modalities against COVID-19
Pharmaceuticals·2020· 26 citedOpen Access
Evidence that miR-152-3p is a positive regulator of SETDB1-mediated H3K9 histone methylation and serves as a toggle between histone and DNA methylation
Experimental Cell Research·2020· 9 cited
Contributors
Elsevier eBooks·2019
Pluripotent cells for the assessment of chemically induced teratogenesis and developmental toxicology
Elsevier eBooks·2019· 2 cited
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Frequent Co-authors

Rudolf Jaenisch(6), Xiao‐bo Zhong(6), Winfried Krueger(6), José E. Manautou(5), Schahram Akbarian(4), Borko Tanasijevic(4), Brenda Milner(3), Mary-Ann Mastrangelo(3), Rahul Bharadwaj(3), Catheryne Whittle(3), Evan Barry(3), Dominic J. Ambrosi(3), Gareth N. Corry(3), Yinghong Ma(3), Jun Wada(2), Anton Wutz(2), Charles L. Branch(2), Raman Bahal(2), Y Hart(2), Frédérick Andermann(2)