Yuichiro Higashimoto

Kurume University — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

38h-index7.8kcitations140works3.72yr avg
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Research Topics

Advanced Glycation End Products research(34), Heme Oxygenase-1 and Carbon Monoxide(30), Hemoglobin structure and function(23), Cancer-related Molecular Pathways(17), Neonatal Health and Biochemistry(11)

Publications140 total

Sulforaphane inhibits cardiac fibrosis induced by advanced glycation end product-receptor axis through its anti-oxidative property
Acta Diabetologica·2025
Heme Regulatory Motif of Heme Oxygenase-2 Is Involved in the Interaction with NADPH–Cytochrome P450 Reductase and Regulates Enzymatic Activity
International Journal of Molecular Sciences·2025· 3 citedOpen Access
Involvement of Mineralocorticoid Receptor Activation by High Mobility Group Box 1 and Receptor for Advanced Glycation End Products in the Development of Acute Kidney Injury
Kidney360·2024· 6 citedOpen Access
Serum Levels of the C-terminal Fragment of Fibroblast Growth Factor 23 (C-FGF23) and Hepcidin in Patients with Hemodialysis Undergoing Treatment with a Proline Hydroxylase Domain (PHD) Inhibitor
Journal of Clinical Nephrology·2024Open Access
DNA Aptamer Raised against Advanced Glycation End Products Improves Sperm Concentration, Motility, and Viability by Suppressing Receptors for Advanced Glycation End Product-Induced Oxidative Stress and Inflammation in the Testes of Diabetic Mice
International Journal of Molecular Sciences·2024· 10 citedOpen Access
DNA Aptamer Raised against Advanced Glycation End Products Improves Sperm Concentration, Motility, and Viability by Suppressing RAGE-Induced Oxidative Stress and Inflammation in Testes of Diabetic Mice
Preprints.org·2024· 3 citedOpen Access
Clinical usefulness of the serum-soluble transferrin receptor in functional iron deficiency associated with long-term hemodialysis
Research Square (Research Square)·2023Open Access
Subcutaneous Infusion of DNA-Aptamer Raised against Advanced Glycation End Products Prevents Loss of Skeletal Muscle Mass and Strength in Accelerated-Aging Mice
Biomedicines·2023· 8 citedOpen Access
Circulating Levels of Fibroblast Growth Factor 23 Selective for C-Terminal (FGF23-CT) in Hemodialysis Patients
Journal of Clinical Nephrology·2023· 1 citedOpen Access
SMTP-44D Inhibits Atherosclerotic Plaque Formation in Apolipoprotein-E Null Mice Partly by Suppressing the AGEs-RAGE Axis
International Journal of Molecular Sciences·2023· 12 citedOpen Access
Heparin and β2-microglobulin amyloidogenesis
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
Heparin and β2-microglobulin amyloidogenesis
GSC Biological and Pharmaceutical Sciences·2023Open Access
PS-B08-8: THERAPEUTIC STRATEGIES TARGETING RAGE IMPROVES RENAL OUTCOME IN LUPUS NEPHRITIS
Journal of Hypertension·2023
Fibroblast growth factor 23 (FGF23) contributes to regulation of hepcidin/ferroportin axis
Proceedings for Annual Meeting of The Japanese Pharmacological Society·2023Open Access
Complex Formation of Heme Oxygenase-2 with Heme Is Competitively Inhibited by the Cytosolic Domain of Caveolin-1
Biochemistry·2021· 2 cited
DNA‐Aptamer Raised against Receptor for Advanced Glycation End Products Improves Survival Rate in Septic Mice
Oxidative Medicine and Cellular Longevity·2021· 4 citedOpen Access
DNA aptamer raised against receptor for advanced glycation end products suppresses renal tubular damage and improves insulin resistance in diabetic mice
Diabetes and Vascular Disease Research·2021· 9 citedOpen Access
Inhibitory effects of RAGE-aptamer on development of monocrotaline-induced pulmonary arterial hypertension in rats
Journal of Cardiology·2020· 6 citedOpen Access
Association of advanced glycation end products with sarcopenia and frailty in chronic kidney disease
Scientific Reports·2020· 62 citedOpen Access
Glyceraldehyde-Derived Pyridinium Evokes Renal Tubular Cell Damage via RAGE Interaction
International Journal of Molecular Sciences·2020· 7 citedOpen Access
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Frequent Co-authors

Ettore Appella(23), Takanori Matsui(14), Sho‐ichi Yamagishi(10), Shinichi Saito(8), Masato Noguchi(8), Carl W. Anderson(6), Kei Fukami(6), Masakazu Sugishima(6), Hiroshi Sakamoto(5), Yuji Ishibashi(5), Hiroyoshi Inoue(5), Keiichi Fukuyama(5), Alessandro Sette(4), Kazuyasu Sakaguchi(4), Seiji Ueda(4), Masayoshi Takeuchi(4), Sho‐ichi Yamagishi(4), Venkatesha Basrur(3), Albert J. Fornace(3), John Sidney(3)