Sylvia C. Stanat

Research Triangle Park Foundation — United States

Medicine · Health Sciences

17h-index3.1kcitations22works0.02yr avg
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Research Topics

Cytomegalovirus and herpesvirus research(19), Herpesvirus Infections and Treatments(14), Viral-associated cancers and disorders(5), HIV Research and Treatment(4), Toxoplasma gondii Research Studies(3)

Publications22 total

Potent and Selective Inhibition of Human Cytomegalovirus Replication by 1263W94, a Benzimidazole <scp>l</scp> -Riboside with a Unique Mode of Action
Antimicrobial Agents and Chemotherapy·2002· 361 citedOpen Access
A Standardized Plaque Reduction Assay for Determination of Drug Susceptibilities of Cytomegalovirus Clinical Isolates
Antimicrobial Agents and Chemotherapy·2000· 148 citedOpen Access
Acyclovir Is Phosphorylated by the Human Cytomegalovirus UL97 Protein
Antimicrobial Agents and Chemotherapy·1999· 103 citedOpen Access
Inhibition of Human Cytomegalovirus DNA Maturation by a Benzimidazole Ribonucleoside Is Mediated through the UL89 Gene Product
Journal of Virology·1998· 192 citedOpen Access
Single amino acid changes in the DNA polymerase confer foscarnet resistance and slow-growth phenotype, while mutations in the UL97-encoded phosphotransferase confer ganciclovir resistance in three double-resistant human cytomegalovirus strains recovered from patients with AIDS
Journal of Virology·1996· 178 citedOpen Access
Analysis Of The Ul97 Phosphotransferase Coding Sequence In Clinical Cytomegalovirus Isolates And Identification Of Mutations Conferring Ganciclovir Resistance
The Journal of Infectious Diseases·1995· 243 cited
Inhibition of HCMV DNA processing by a new class of anti-HCMV compounds (benzimidazole ribosides) is mediated through the UL89 gene product
Antiviral Research·1995· 3 cited
A three-nucleotide deletion in the UL97 open reading frame is responsible for the ganciclovir resistance of a human cytomegalovirus clinical isolate
Journal of Virology·1995· 111 citedOpen Access
A point mutation in the human cytomegalovirus DNA polymerase gene confers resistance to ganciclovir and phosphonylmethoxyalkyl derivatives
Antimicrobial Agents and Chemotherapy·1993· 176 cited
A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells
Nature·1992· 476 cited
Ganciclovir-resistant cytomegalovirus clinical isolates: mode of resistance to ganciclovir
Antimicrobial Agents and Chemotherapy·1991· 170 citedOpen Access
Resistance of HCMV to DHPG, HPMPC and HPMPA mapped to the viral DNA polymerase gene
Antiviral Research·1991· 4 cited
Acyclovir‐resistant varicella zoster virus infection after chronic oral acyclovir therapy in patients with the acquired immunodeficiency syndrome (AIDS)
International Journal of Gynecology & Obstetrics·1990· 15 cited
Rapid antiviral DNA-DNA hybridization assay for human cytomegalovirus
Journal of Virological Methods·1990· 73 cited
Progressive Disease Due to Ganciclovir-Resistant Cytomegalovirus in Immunocompromised Patients
New England Journal of Medicine·1989· 408 cited
A human cytomegalovirus mutant resistant to the nucleoside analog 9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine (BW B759U) induces reduced levels of BW B759U triphosphate.
Proceedings of the National Academy of Sciences·1986· 154 cited
Murine cytomegalovirus infection of mouse testes
Journal of Virology·1986· 18 citedOpen Access
Congenital Defects due to Reactivation of Latent Murine Cytomegaloviral Infection During Pregnancy
The Journal of Infectious Diseases·1985· 17 cited
Metabolic activation of the nucleoside analog 9-[( 2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine in human diploid fibroblasts infected with human cytomegalovirus.
Proceedings of the National Academy of Sciences·1985· 236 citedOpen Access
Murine Cytomegalovirus-Induced Congenital Defects and Fetal Maldevelopment
The Journal of Infectious Diseases·1983· 28 cited
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Frequent Co-authors

Karen K. Biron(16), Christine L. Talarico(7), Donald M. Coen(5), Alejo Erice(4), J. F. Baskar(4), Veronica Sullivan(3), M. Davis(3), John C. Drach(3), Sunwen Chou(2), M. Colin Jordan(2), Richard J. Harvey(2), Michelle G. Davis(2), Wayne H. Miller(2), Leroy B. Townsend(2), Szu‐Yi Chou(2), J B Sorrell(2), James A. Fyfe(2), C U Lambe(2), Mark Underwood(2), Fausto Baldanti(2)