Akul Singhania

Tempus Labs (United States) — United States

Medicine · Health Sciences

23h-index2.3kcitations52works0.02yr avg
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Research Topics

Tuberculosis Research and Epidemiology(16), Mycobacterium research and diagnosis(10), Asthma and respiratory diseases(8), HIV Research and Treatment(5), Immune Cell Function and Interaction(5)

Publications52 total

Abstract 4589: Molecular subtypes identified in lung adenocarcinoma using a large-scale, real-world dataset
Cancer Research·2025
Single-cell profiling reveals distinct subsets of CD14+ monocytes drive blood immune signatures of active tuberculosis
Frontiers in Immunology·2023· 31 citedOpen Access
Profiling the myeloid compartment of PBMC in active tuberculosis reveals substantial changes in CD14+ cells and upregulation of CD16 in pro-inflammatory dendritic cells
The Journal of Immunology·2022
CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition
Nature·2022· 200 citedOpen Access
CD4+CCR6+ T cells dominate the BCG-induced transcriptional signature
EBioMedicine·2021· 20 citedOpen Access
S93 Correlation of eotaxin-3 gene expression and other IL-13-induced genes in patients with asthma
2021Open Access
A metric for evaluating biological information in gene sets and its application to identify co-expressed gene clusters in PBMC
PLoS Computational Biology·2021· 4 citedOpen Access
Distinct blood transcriptomic signature of treatment in latent tuberculosis infected individuals at risk of developing active disease
Tuberculosis·2021· 25 citedOpen Access
Correlation of eotaxin-3 gene expression and other IL-13-induced genes in patients with asthma
2021· 2 cited
CD4+CCR6+ T cells dominate the BCG-induced transcriptional signature
2021· 1 citedOpen Access
Blood transcriptomics reveal the evolution and resolution of the immune response in tuberculosis
The Journal of Experimental Medicine·2021· 78 citedOpen Access
HLA-DR Marks Recently Divided Antigen-Specific Effector CD4 T Cells in Active Tuberculosis Patients
The Journal of Immunology·2021· 70 citedOpen Access
CCNE1 amplification is synthetic-lethal with PKMYT1 kinase inhibition
2021· 22 citedOpen Access
The TCR repertoire of α-synuclein-specific T cells in Parkinson’s disease is surprisingly diverse
Scientific Reports·2021· 36 citedOpen Access
Blood Transcriptional Phenotypes of Progressive Latent <i>M. tuberculosis</i> Infection Inform Novel Signatures That Improve Prediction of Tuberculosis Risk
SSRN Electronic Journal·2021Open Access
An In-Depth Comparison of Latent HIV-1 Reactivation in Multiple Cell Model Systems and Resting CD4+ T Cells from Aviremic Patients
UNC Libraries·2020Open Access
Dose-responsive gene expression in suberoylanilide hydroxamic acid-treated resting CD4+ T cells
UNC Libraries·2020Open Access
Upregulation of epithelial metallothioneins by metal-rich ultrafine particulate matter from an underground railway
Metallomics·2020· 10 citedOpen Access
Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis
Nature Immunology·2020· 138 citedOpen Access
LSC - 2019 - Novel cellular effects of ultrafine particulate matter from an underground railway station uncovered through RNAseq
2019
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Frequent Co-authors

Christopher H. Woelk(23), Anne O’Garra(9), Pranabashis Haldar(8), Bjoern Peters(8), Christine M. Graham(7), Raman Verma(6), Ratko Djukanović(6), Peter Howarth(6), Paige Dubelko(6), Celsa A. Spina(5), Marc Rodrigue(5), Gerrit Woltmann(5), Timothy Hinks(5), Cecilia S. Lindestam Arlehamn(5), Grégory Seumois(5), Alessandro Sette(5), Nadejda Beliakova‐Bethell(5), David M. Margolis(4), Philippe Leissner(4), Daniel Horowitz(4)