Luke H. Chao

Harvard University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index1.8kcitations64works9.72yr avg
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Research Topics

Mitochondrial Function and Pathology(14), ATP Synthase and ATPases Research(12), Mosquito-borne diseases and control(8), Photosynthetic Processes and Mechanisms(8), Neuroscience and Neuropharmacology Research(7)

Publications64 total

Treatment of a severe vascular disease using a bespoke CRISPR–Cas9 base editor in mice
Nature Biomedical Engineering·2025· 6 citedOpen Access
Stress-mediated growth determines <i>Escherichia coli</i> division site morphogenesis
Proceedings of the National Academy of Sciences·2025Open Access
Ancestral sequence reconstruction of the Mic60 Mitofilin domain reveals residues supporting respiration in yeast
Protein Science·2025· 3 citedOpen Access
SARM1 loss protects retinal ganglion cells in a mouse model of autosomal dominant optic atrophy
Journal of Clinical Investigation·2025· 4 citedOpen Access
Contemporary insights into elamipretide’s mitochondrial mechanism of action and therapeutic effects
Biomedicine & Pharmacotherapy·2025· 11 citedOpen Access
The aPBP-type cell wall synthase PBP1b plays a specialized role in fortifying the <i>Escherichia coli</i> division site against osmotic rupture
2025· 7 citedOpen Access
<i>In vivo</i> Treatment of a Severe Vascular Disease via a Bespoke CRISPR-Cas9 Base Editor
2024· 2 citedOpen Access
Loss of SARM1 protects against retinal ganglion cell degeneration in Autosomal Dominant Optic Atrophy
2024· 1 citedOpen Access
Stress-mediated growth determines <i>E. coli</i> division site morphogenesis
2024· 1 citedOpen Access
Identification of SLC25A46 interaction interfaces with mitochondrial membrane fusogens Opa1 and Mfn2
Journal of Biological Chemistry·2024· 9 citedOpen Access
Prominin 1 and Tweety Homology 1 both induce extracellular vesicle formation
eLife·2024· 3 citedOpen Access
Click editing enables programmable genome writing using DNA polymerases and HUH endonucleases
Nature Biotechnology·2024· 57 citedOpen Access
Author response: Prominin 1 and Tweety Homology 1 both induce extracellular vesicle formation
2024Open Access
Author Reply to Peer Reviews of Prominin 1 and Tweety Homology 1 both induce extracellular vesicle formation
2024
Ancestral sequence reconstruction of the Mic60 Mitofilin domain reveals residues supporting respiration in yeast
2024· 3 citedOpen Access
In situ architecture of Opa1-dependent mitochondrial cristae remodeling
The EMBO Journal·2024· 47 citedOpen Access
Helical reconstruction of VP39 reveals principles for baculovirus nucleocapsid assembly
Nature Communications·2024· 11 citedOpen Access
Identification of SLC25A46 interaction interfaces with mitochondrial membrane fusogens Opa1 and Mfn2
2023· 3 citedOpen Access
Prominin 1 and Tweety Homology 1 both induce extracellular vesicle formation
2023Open Access
Helical reconstruction of VP39 reveals principles for baculovirus nucleocapsid assembly
2023· 1 citedOpen Access
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Frequent Co-authors

Margaret M. Stratton(10), Yifan Ge(10), Sivakumar Boopathy(10), John Kuriyan(9), Howard Schulman(8), Julie L. McDonald(8), Paula P. Navarro(7), Friederike M. C. Benning(7), Il‐Hyung Lee(6), Jay T. Groves(6), Adam W. Smith(6), Camila Makhlouta Lugo(6), Benjamin P. Kleinstiver(6), Tran H. Nguyen(6), Xiaojun Shi(5), Ananda VY(5), Stephen C. Harrison(5), Pusparanee Hakim(5), Bridget E Luce(5), Moitrayee Bhattacharyya(4)