Peter Lotfy

Broad Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index2.5kcitations19works29.72yr avg
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Research Topics

CRISPR and Genetic Engineering(8), RNA and protein synthesis mechanisms(7), Antifungal resistance and susceptibility(3), Viral Infections and Immunology Research(3), Neuroinflammation and Neurodegeneration Mechanisms(3)

Publications19 total

Multi-modal choroid plexus pathology in aging and Alzheimer’s disease
2025· 1 citedOpen Access
The choroid plexus synergizes with immune cells during neuroinflammation
Cell·2024· 87 citedOpen Access
An enhanced IL17 and muted type I interferon nasal epithelial cell state characterizes severe COVID-19 with fungal coinfection
Microbiology Spectrum·2024· 1 citedOpen Access
Deep learning and CRISPR-Cas13d ortholog discovery for optimized RNA targeting
Cell Systems·2023· 55 cited
A collaboration between immune cells and the choroid plexus epithelium in brain inflammation
2023· 1 citedOpen Access
Severe COVID-19 is associated with fungal colonization of the nasopharynx and potent induction of IL-17 responses in the nasal epithelium
2022· 2 citedOpen Access
Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome
Nature Biotechnology·2022· 188 citedOpen Access
Genome Editing with CRISPR‐Cas Systems
2022
Meta-genomic detection of Candida spp. in the nasopharynx and upper airway of patients with severe COVID-19
The Journal of Immunology·2022
Large-scale discovery of recombinases for integrating DNA into the human genome
2021· 10 citedOpen Access
Deep learning and CRISPR-Cas13d ortholog discovery for optimized RNA targeting
2021· 18 citedOpen Access
More than just content: building community in the graduate classroom
Nature Biotechnology·2021· 5 citedOpen Access
Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19
Cell·2021· 337 citedOpen Access
Barcoded viral tracing of single-cell interactions in central nervous system inflammation
Science·2021· 264 citedOpen Access
Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19
2021· 58 citedOpen Access
Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d
Cell·2018· 278 citedOpen Access
Structural basis for the RNA-guided ribonuclease activity of CRISPR-Cas13d
2018· 3 citedOpen Access
Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors
Cell·2018· 1.2k citedOpen Access
Elucidating the role of autophagy in the clearance of phosphorylated tau protein in human neurons
eScholarship (California Digital Library)·2016Open Access

Frequent Co-authors

Patrick D. Hsu(8), Haley B. Williams(7), José Ordovás-Montañés(7), Silvana Konermann(5), Vincent N. Miao(5), Anna H. Owings(5), Andrew W. Navia(5), Joshua D. Bromley(5), Meredith Sloan(5), Hannah Laird(5), Micayla George(5), George Abraham(5), Michal Šenitko(5), Sarah C. Glover(5), Carly G.K. Ziegler(4), Ying Tang(4), Riley S. Drake(4), Yilianys Pride(4), Tanya O. Robinson(4), Alex K. Shalek(4)