Silvana Konermann

American Institute of Mathematics — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

24h-index22.7kcitations58works20.22yr avg
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Research Topics

CRISPR and Genetic Engineering(38), RNA and protein synthesis mechanisms(21), Advanced biosensing and bioanalysis techniques(10), Single-cell and spatial transcriptomics(8), Cell Image Analysis Techniques(8)

Publications58 total

Site-specific DNA insertion into the human genome with engineered recombinases
Nature Biotechnology·2025· 3 citedOpen Access
Megabase-scale human genome rearrangement with programmable bridge recombinases
Science·2025· 14 cited
Mouse lemur cell atlas informs primate genes, physiology and disease
Nature·2025· 4 citedOpen Access
A molecular cell atlas of mouse lemur, an emerging model primate
Nature·2025· 7 citedOpen Access
Predicting cellular responses to perturbation across diverse contexts with State
2025· 34 citedOpen Access
Megabase-scale human genome rearrangement with programmable bridge recombinases
2025· 5 citedOpen Access
Site-specific DNA insertion into the human genome with engineered recombinases
2024· 7 citedOpen Access
A combinatorial domain screening platform reveals epigenetic effector interactions for transcriptional perturbation
2024· 4 citedOpen Access
Bridge RNAs direct programmable recombination of target and donor DNA
Nature·2024· 108 citedOpen Access
Structural mechanism of bridge RNA-guided recombination
Nature·2024· 55 citedOpen Access
An organism-wide atlas of hormonal signaling based on the mouse lemur single-cell transcriptome
Nature Communications·2024· 10 citedOpen Access
Rewriting endogenous human transcripts with <i>trans</i> -splicing
2024· 4 citedOpen Access
Bridge RNAs direct modular and programmable recombination of target and donor DNA
2024· 7 citedOpen Access
Deep learning and CRISPR-Cas13d ortholog discovery for optimized RNA targeting
Cell Systems·2023· 55 cited
The KDM6A-KMT2D-p300 axis regulates susceptibility to diverse coronaviruses by mediating viral receptor expression
PLoS Pathogens·2023· 8 citedOpen Access
DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner
PLoS Biology·2023· 22 citedOpen Access
Kinase-independent activity of DYRK1A promotes viral entry of highly pathogenic human coronaviruses
2022Open Access
Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection
Nature Genetics·2022· 134 citedOpen Access
Adversarial domain translation networks for integrating large-scale atlas-level single-cell datasets
Nature Computational Science·2022· 44 cited
Deep learning and CRISPR-Cas13d ortholog discovery for optimized RNA targeting
2021· 18 citedOpen Access
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Frequent Co-authors

Patrick D. Hsu(31), Feng Zhang(15), Jonathan S. Gootenberg(15), Omar O. Abudayyeh(13), Julia Joung(12), Hiroshi Nishimasu(9), Matthew G. Durrant(9), Alexandro E. Trevino(8), Mark D. Brigham(8), April Pawluk(8), Connor V. Duffy(7), Randall J. Platt(6), F. Ann Ran(5), Neville E. Sanjana(5), Peter Lotfy(5), Nicholas T. Perry(5), James J. Pai(5), Masahiro Hiraizumi(5), David Scott(4), Osamu Nureki(4)