Feng Zhang

Broad Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

101h-index129.4kcitations287works8.72yr avg
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Research Topics

CRISPR and Genetic Engineering(183), RNA and protein synthesis mechanisms(76), Advanced biosensing and bioanalysis techniques(63), RNA regulation and disease(30), RNA Interference and Gene Delivery(26)

Publications286 total

Transient hepatic reconstitution of trophic factors enhances aged immunity
Nature·2025· 2 citedOpen Access
Rheological model of SiC-reinforced cemented tailings backfill and its thermodynamic responses to deep in-situ conditions
Powder Technology·2025
An updated evolutionary classification of CRISPR–Cas systems including rare variants
Nature Microbiology·2025· 17 citedOpen Access
A synthetic transcription cascade enables direct in planta shoot regeneration for transgenesis and gene editing in multiple plants
Molecular Plant·2025· 5 citedOpen Access
DExD-box helicase 39 A, targeted by coumestrol, facilitates the malignant behaviors of osteosarcoma cells
Hereditas·2025Open Access
In situ directed evolution of γ-glutamyl kinase in Corynebacterium glutamicum S9114 by innovative EvolvR-mediated mutagenesis and rare codon-based selection to increase L-proline production
Biochemical Engineering Journal·2025
Cryo-EM micrographs of PbAbiF dimer bound to ncRNA
EMPIAR dataset·2025Open Access
Healthcare function differences between Ziqin & Kujin (Scutellaria baicalensis): Role of component proportions
Applied Food Research·2025· 1 citedOpen Access
Targeted delivery of diverse biomolecules with engineered bacterial nanosyringes
Nature Biotechnology·2025· 7 citedOpen Access
Tissue architecture dynamics underlying immune development and decline in the thymus
2025· 2 citedOpen Access
Structure and biochemistry-guided engineering of an all-RNA system for DNA insertion with R2 retrotransposons
Nature Communications·2025· 3 citedOpen Access
Weakening behaviour of water saturated Island coal body subjected to SHPB tests
Scientific Reports·2025· 1 citedOpen Access
Characterizing protein sequence determinants of nuclear condensates by high-throughput pooled imaging with CondenSeq
Nature Methods·2025· 5 citedOpen Access
Evolution-guided protein design of IscB for persistent epigenome editing in vivo
Nature Biotechnology·2025· 16 citedOpen Access
Cryo-EM micrographs of TIGR-TasR in complex with tigRNA and target DNA after DNA cleavage
EMPIAR dataset·2025Open Access
m6A deficiency impairs hypothalamic neurogenesis of feeding-related neurons in mice and human organoids and leads to adult obesity in mice
Cell stem cell·2025· 6 citedOpen Access
Developmental regulators enable rapid and efficient soybean transformation and CRISPR-mediated genome editing
2025· 2 citedOpen Access
TIGR-Tas: A family of modular RNA-guided DNA-targeting systems in prokaryotes and their viruses
Science·2025· 30 citedOpen Access
Rational engineering of minimally immunogenic nucleases for gene therapy
Nature Communications·2025· 32 citedOpen Access
Novel multitarget-labeled molecular networking for exploring pharmacodynamic compounds of traditional Chinese medicine formulae: a case study of Zhu-Ling decoction
Analytical Methods·2025
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Frequent Co-authors

Jonathan S. Gootenberg(17), Omar O. Abudayyeh(15), Eugene V. Koonin(11), David Scott(10), Kira S. Makarova(10), F. Ann Ran(9), Patrick D. Hsu(9), Silvana Konermann(9), Julia Joung(9), Le Cong(8), David Cox(7), Neville E. Sanjana(7), Aviv Regev(7), Ophir Shalem(6), Bernd Zetsche(6), Winston X. Yan(6), Naomi Habib(5), Hiroshi Nishimasu(5), Osamu Nureki(5), Max J. Kellner(5)