Farah Sheikh

Greater Manchester Mental Health NHS Foundation Trust — United Kingdom

Medicine · Health Sciences

37h-index5.7kcitations142works0.82yr avg
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Research Topics

Cardiovascular Effects of Exercise(49), Cardiomyopathy and Myosin Studies(48), Cardiac electrophysiology and arrhythmias(17), Muscle Physiology and Disorders(13), Fibroblast Growth Factor Research(11)

Publications140 total

Abstract 4371137: Mechanisms of Heart Failure Induced by Myofilament Mutations: Disruption of mRNA Stability and Expression?
Circulation·2025
Disease penetrance and phenotypic spectrum of desmoplakin variant carriers in the population
Heart Rhythm·2025
Abstract Fri009: Connexin-43 Gene Therapy Targets Desmosomal Gene Expression To Rescue Cardiac End-Stage Deficits in Mouse and Human Models of Arrhythmogenic Cardiomyopathy
Circulation Research·2025· 1 cited
Association of RhoGEF Ect2 with Desmoplakin Supports RhoA Activity at Intercellular Junctions: Implications for Carvajal Disease
2025Open Access
<i>TMEM</i> -ing the Tide: Gene Therapy Holds Promise for ARVC5
Circulation Research·2025
Preclinical efficacy and safety of AAVrh10-based plakophilin-2 gene therapy (LX2020) as a treatment for arrhythmogenic cardiomyopathy
npj Regenerative Medicine·2025· 4 citedOpen Access
Utility of Computational Models in Predicting the Efficacy of Stem Cell Therapy for Schizophrenia – Insights from a Systematic Review and Meta-Analysis
European Psychiatry·2025Open Access
Taxing Hearts: <i>TAX1BP3</i> Loss Stirs Up TRPV4 Channels in Arrhythmogenic Cardiomyopathy
Circulation Research·2025
Risk of Proton Pump Inhibitor (PPI)-Induced Galactorrhea: An Uncommon Adverse Effect of a Common Drug
Cureus·2025· 1 citedOpen Access
Combined Loss of Obsc and Obsl1 in Murine Hearts Results in Diastolic Dysfunction, Altered Metabolism, and Deregulated Mitophagy
Circulation Heart Failure·2025· 3 citedOpen Access
Abstract 4146762: Cardiac Inflammation as a Key Driver of Desmoplakin-Mediated Cardiomyopathy: Insights from a Novel Animal Model
Circulation·2024· 2 cited
Rapid diagnosis of herpes simplex virus 1 and 2 bloodstream infections utilizing a sample-to-answer platform
Journal of Clinical Microbiology·2024· 1 citedOpen Access
Abstract We117: Preclinical Evidence of Long-term Efficacy and Safety of LX2020, an AAV based Plakophilin-2 Gene Therapy, for the Treatment of Arrhythmogenic Cardiomyopathy
Circulation Research·2024
Cardiomyocyte-specific deletion of adhesion G protein-coupled receptor F5 (ADGRF5) increases susceptibility to stress and arrhythmia
Journal of Pharmacology and Experimental Therapeutics·2024
Cardiomyocyte-specific deletion of adhesion G protein-coupled receptor F5 (ADGRF5) increases susceptibility to stress and arrhythmia
Physiology·2024
Plakophilin 2 gene therapy prevents and rescues arrhythmogenic right ventricular cardiomyopathy in a mouse model harboring patient genetics
Nature Cardiovascular Research·2023· 63 citedOpen Access
Abstract 18583: Preclinical Efficacy and Safety of Intravenously Administered LX2020 Gene Therapy for the Treatment of Arrhythmogenic Cardiomyopathy
Circulation·2023
Editorial
Life Sciences·2023
Recurrent Myocarditis in Patients With Desmosomal Pathogenic Variants
JACC. Clinical electrophysiology·2023· 5 citedOpen Access
Psychosocial Outcomes in Children with Cleft Lip and/or Palate: Associations of Demographic, Cleft Morphologic, and Treatment-Related Variables
The Cleft Palate-Craniofacial Journal·2023· 20 cited
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Frequent Co-authors

Ju Chen(15), Robert C. Lyon(12), Yusu Gu(9), Kirk L. Peterson(9), Stephan Lange(8), Nancy D. Dalton(7), Andrew D. McCulloch(6), Peter A. Cattini(6), Jeffrey H. Omens(5), Sylvia Μ. Evans(5), Yan Liang(5), Fabian Zanella(4), Valeria Mezzano(4), Jason Pellman(4), Kunfu Ouyang(4), Hongqiang Cheng(4), Karen L. Christman(3), Andrea A. Domenighetti(3), Xingqun Liang(3), William H. Bradford(3)