Hanny Klaasse Bos

Academic Medical Center — Netherlands

Medicine · Health Sciences

7h-index278citations9works0.02yr avg
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Research Topics

Cytokine Signaling Pathways and Interactions(5), T-cell and B-cell Immunology(3), Immune Cell Function and Interaction(3), NF-κB Signaling Pathways(2), Protein Kinase Regulation and GTPase Signaling(1)

Publications9 total

Human B cells promote T-cell plasticity to optimize antibody response by inducing coexpression of TH1/TFH signatures
Journal of Allergy and Clinical Immunology·2014· 27 cited
Response: priming of human naive CD4+ T cells via CD5 costimulation requires IL-6 for optimal Th17 development
Blood·2012Open Access
CD5 costimulation induces stable Th17 development by promoting IL-23R expression and sustained STAT3 activation
Blood·2011· 47 citedOpen Access
Antigen-Specific B Cells Reactivate an Effective Cytotoxic T Cell Response against Phagocytosed Salmonella through Cross-Presentation
PLoS ONE·2010· 58 citedOpen Access
Identification of residues in the putative 5th helical region of human interleukin‐6, important for activation of the IL‐6 signal transducer, gp130
FEBS Letters·1996· 6 citedOpen Access
Identification of Single Amino Acid Residues of Human IL-6 Involved in Receptor Binding and Signal Initiation
Journal of Interferon & Cytokine Research·1996· 31 cited
Leucine‐58 in the putative 5th helical region of human interleukin (IL)‐6 is important for activation of the IL‐6 signal transducer, gp130
FEBS Letters·1995· 12 citedOpen Access
Combining Two Mutations of Human Interleukin-6 That Affect gp130 Activation Results in a Potent Interleukin-6 Receptor Antagonist on Human Myeloma Cells
Journal of Biological Chemistry·1995· 46 citedOpen Access
Development of an interleukin (IL) 6 receptor antagonist that inhibits IL-6-dependent growth of human myeloma cells.
The Journal of Experimental Medicine·1994· 51 citedOpen Access

Frequent Co-authors

Stefan Rose‐John(5), Jelle de Wit(4), Yuri Souwer(4), Tineke Jorritsma(4), S. Marieke van Ham(4), Just P. J. Brakenhoff(4), Joachim Grötzinger(4), Floris D. de Hon(3), Marc Ehlers(3), Jacques Neefjes(2), Femke J. M. Muller(2), Martien L. Kapsenberg(2), Esther C. de Jong(2), Günther Kurapkat(2), Lucien A. Aarden(2), Anja ten Brinke(1), S B Ebeling(1), L Aarden(1), Astrid J. van Beelen(1), Rosa de Groot(1)