Charles Pyke

Novo Nordisk (Denmark) — Denmark

Biochemistry, Genetics and Molecular Biology · Life Sciences

46h-index9.8kcitations121works12.02yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Protease and Inhibitor Mechanisms(33), Diabetes Treatment and Management(28), HER2/EGFR in Cancer Research(15), Monoclonal and Polyclonal Antibodies Research(15), Cell Adhesion Molecules Research(14)

Publications121 total

Liraglutide upregulates the <i>Cftr</i> gene and regulates the mucus transcriptome profile in Brunner's glands in mice
Clinical and Translational Medicine·2025Open Access
Integrative single-cell and genetic profiling of human heart failure identifies targets for cardiomyocyte restoration
2025Open Access
Mapping atherogenesis mechanisms in smooth muscle cells by targeting genes linked to coronary artery disease
iScience·2025· 1 citedOpen Access
Author Correction: A comprehensive spatio-cellular map of the human hypothalamus
Nature·2025· 1 citedOpen Access
A comprehensive spatio-cellular map of the human hypothalamus
Nature·2025· 59 citedOpen Access
Mapping Atherogenesis Mechanisms in Smooth Muscle Cells by Targeting Genes Linked to Coronary Artery Disease
SSRN Electronic Journal·2025Open Access
Encompassing view of spatial and single-cell RNA sequencing renews the role of the microvasculature in human atherosclerosis
Nature Cardiovascular Research·2024· 39 citedOpen Access
<i>Glp1r-Lepr</i> coexpressing neurons modulate the suppression of food intake and body weight by a GLP-1/leptin dual agonist
Science Translational Medicine·2024· 21 cited
Mapping atherogenesis mechanisms in smooth muscle cells by targeting genes linked to coronary artery disease
2024· 1 citedOpen Access
Smooth muscle-specific deletion of cellular communication network factor 2 causes severe aorta malformation and atherosclerosis
Cardiovascular Research·2024· 2 citedOpen Access
A systematic evaluation of state-of-the-art deconvolution methods in spatial transcriptomics: insights from cardiovascular disease and chronic kidney disease
Frontiers in Bioinformatics·2024· 8 citedOpen Access
Encompassing view of spatial and single-cell RNA-seq renews the role of the microvasculature in human atherosclerosis
2023· 4 citedOpen Access
A Benchmark of state-of-the-art Deconvolution Methods in Spatial Transcriptomics: Insights from Cardiovascular Disease and Chronic Kidney Disease
2023Open Access
Human HYPOMAP: A comprehensive spatio-cellular map of the human hypothalamus
2023· 8 citedOpen Access
A Lipopolysaccharide Mouse Model Mirrors Neuroinflammatory Transcriptional Signatures of Human AD, and the Glucagon-Like Peptide-1 Receptor Agonist Semaglutide Attenuates Neuroinflammation in this Model (P1-6.007)
Neurology·2023· 1 cited
Data from Sym004: A Novel Synergistic Anti–Epidermal Growth Factor Receptor Antibody Mixture with Superior Anticancer Efficacy
2023Open Access
Supplementary Figure 2 from Sym004: A Novel Synergistic Anti–Epidermal Growth Factor Receptor Antibody Mixture with Superior Anticancer Efficacy
2023Open Access
Supplementary Table 1 from Sym004: A Novel Synergistic Anti–Epidermal Growth Factor Receptor Antibody Mixture with Superior Anticancer Efficacy
2023Open Access
Supplementary Figure 3 from Sym004: A Novel Synergistic Anti–Epidermal Growth Factor Receptor Antibody Mixture with Superior Anticancer Efficacy
2023Open Access
Supplementary Figure 3 from Sym004: A Novel Synergistic Anti–Epidermal Growth Factor Receptor Antibody Mixture with Superior Anticancer Efficacy
2023Open Access
page 1 of 7Next →

Frequent Co-authors

Lotte Bjerre Knudsen(17), Keld Danø(17), Leif R. Lund(12), Elisabeth Ralfkiær(8), Anna Secher(7), John Rømer(7), Peter Kristensen(7), Niels Vrang(6), Jens Eriksen(6), Jacob Jelsing(5), Pernille Barkholt(5), Karl Tryggvason(4), Boye Schnack Nielsen(4), Ebbe Rønne(4), Henrik H. Hansen(4), Katrine Fabricius(4), Arian F. Baquero(3), Kevin L. Grove(3), Kirsten Raun(3), Sarah Juel Paulsen(3)