Ganes C. Sen

University of North Carolina at Chapel Hill — United States

Immunology and Microbiology · Life Sciences

80h-index21.8kcitations329works1.82yr avg
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Research Topics

interferon and immune responses(151), RNA regulation and disease(68), Cytokine Signaling Pathways and Interactions(55), Immune Response and Inflammation(40), RNA and protein synthesis mechanisms(38)

Publications328 total

IRF3-mediated pathogenicity in a murine model of human hepatitis A
UNC Libraries·2025Open Access
TLR9 signaling requires ligand-induced phosphorylation of two specific tyrosine residues by EGFR and Syk
mBio·2025· 1 citedOpen Access
TLR9 signaling requires ligand-induced phosphorylation of two specific tyrosine residues by EGFR and Syk
2024· 1 citedOpen Access
The interferon-induced protein, IFIT2, requires RNA-binding activity and neuronal expression to protect mice from intranasal vesicular stomatitis virus infection
mBio·2024· 7 citedOpen Access
The Epiphytic Flowering Plants of Darjeeling Hills, Other than Orchids
Nelumbo·2024· 2 citedOpen Access
Inflammatory Cytokines Can Induce Synthesis Of Type-I Interferon
2024Open Access
Cell-type-specific need of Ddx3 and PACT for interferon induction by RNA viruses
Journal of Virology·2023· 8 citedOpen Access
Interferon induction by <scp>STING</scp> requires its translocation to the late endosomes
Traffic·2023· 7 citedOpen Access
Ifit2 restricts murine coronavirus spread to the spinal cord white matter and its associated myelin pathology
Journal of Virology·2023· 6 citedOpen Access
EGF-Receptor–Dependent TLR7 Signaling in Macrophages Promotes Glomerular Injury in Crescentic Glomerulonephritis
Laboratory Investigation·2023· 4 citedOpen Access
Unexpected Need of the Epidermal Growth Factor Receptor Tyrosine Kinase Activity for Signaling by Intracellular Pattern Recognition Receptors of Nucleic Acids
Journal of Interferon & Cytokine Research·2023Open Access
STAT2 hinders STING intracellular trafficking and reshapes its activation in response to DNA damage
Proceedings of the National Academy of Sciences·2023· 17 citedOpen Access
IFN-Induced Protein with Tetratricopeptide Repeats 2 Limits Autoimmune Inflammation by Regulating Myeloid Cell Activation and Metabolic Activity
The Journal of Immunology·2023· 5 citedOpen Access
Type I interferon signaling facilitates resolution of acute liver injury by priming macrophage polarization
Cellular and Molecular Immunology·2023· 37 citedOpen Access
Intracranial delivery of antisense locked nucleic acids for silencing microRNAs in the mouse brain
STAR Protocols·2022Open Access
IRF3 inhibits nuclear translocation of NF-κB to prevent viral inflammation
Proceedings of the National Academy of Sciences·2022· 49 citedOpen Access
Ifit2 regulates murine-coronavirus spread to the spinal cord white matter and its associated myelin pathology
2022Open Access
PACT establishes a posttranscriptional brake on mitochondrial biogenesis by promoting the maturation of miR-181c
Journal of Biological Chemistry·2022· 7 citedOpen Access
IFN-induced protein with tetratricopeptide repeats 2 (Ifit2) limits autoimmune inflammation by regulating myeloid cell activation and metabolic activity
2022Open Access
STING-Mediated Interferon Induction by Herpes Simplex Virus 1 Requires the Protein Tyrosine Kinase Syk
mBio·2021· 29 citedOpen Access
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Frequent Co-authors

Volker Fensterl(6), George R. Stark(5), Péter Lengyel(5), Saumendra N. Sarkar(5), Kristi L. Peters(5), Xiaoxia Li(4), Saurabh Chattopadhyay(4), Bryan Williams(4), Michael Gale(3), Michael Diamond(3), Shoudong Li(3), Daniel J. Hui(3), Fulvia Terenzi(3), Robert H. Silverman(2), Kristy J. Szretter(2), Ji-Young Min(2), Robert M. Krug(2), Bartolomé Cabrer(2), Katarzyna Bulek(2), Thomas A. Hamilton(2)