Daniel J. Hui

Easton Hospital — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

21h-index4.2kcitations50works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Virus-based gene therapy research(30), CAR-T cell therapy research(18), Viral Infectious Diseases and Gene Expression in Insects(7), Immunotherapy and Immune Responses(6), RNA Interference and Gene Delivery(6)

Publications50 total

High-throughput method to analyze the cytotoxicity of CAR T Cells in a 3D tumor spheroid model using image cytometry
The Journal of Immunology·2023Open Access
Abstract 4575: High-throughput method to analyze the cytotoxicity of CAR T cells in a 3D tumor spheroid model using image cytometry
Cancer Research·2023
Quantifying factors that affect polygenic risk score performance across diverse ancestries and age groups for body mass index
2022· 2 citedOpen Access
TmPSMA-02: A CD2 endodomain containing double armored PSMA CAR T with enhanced efficacy and lower immune toxicity.
Journal of Clinical Oncology·2022· 4 cited
{If your bait can sing the wild one will come} Like Shadows Through Leaves by the Migrant Ecologies Project: Oberhausen ISFF International Competition 2021 Official Selection
2021
Safety of AAV Factor IX Peripheral Transvenular Gene Delivery to Muscle in Hemophilia B Dogs
UNC Libraries·2020Open Access
Integrated skin transcriptomics and serum multiplex assays reveal novel mechanisms of wound healing in diabetic foot ulcers
2020Open Access
Integrated skin transcriptomics and serum multiplex assays reveal novel mechanisms of wound healing in diabetic foot ulcers
2020· 5 citedOpen Access
LAIT: a local ancestry inference toolkit
UNC Libraries·2019Open Access
A Phase 1/2 Trial of Investigational Spk-8011 in Hemophilia a Demonstrates Durable Expression and Prevention of Bleeds
Blood·2018· 57 cited
Hemophilia B Gene Therapy with a High-Specific-Activity Factor IX Variant
New England Journal of Medicine·2017· 736 citedOpen Access
Spk-9001: Adeno-Associated Virus Mediated Gene Transfer for Hemophilia B Achieves Sustained Mean Factor IX Activity Levels of >30% without Immunosuppression
Blood·2016· 19 cited
185. Safety Study by Validated Immunoassays in a Phase III Study of Subjects with Inherited Retinal Dystrophy Due to Mutations in the Gene Encoding Human Retinal Pigment Epithelium-Specific Protein 65 (RPE65) Injected with Adeno-Associated Viral Vectors
Molecular Therapy·2016· 1 citedOpen Access
AAV capsid CD8+ T-cell epitopes are highly conserved across AAV serotypes
Molecular Therapy — Methods & Clinical Development·2015· 81 citedOpen Access
Overcoming Preexisting Humoral Immunity to AAV Using Capsid Decoys
Science Translational Medicine·2013· 336 citedOpen Access
Modulation of CD8+ T cell responses to AAV vectors with IgG-derived MHC class II epitopes
Molecular Therapy·2013· 42 citedOpen Access
Enhanced T Cell Function in a Mouse Model of Human Glycosylation
The Journal of Immunology·2013· 21 citedOpen Access
A Novel Strategy to Circumvent Pre-Existing Humoral Immunity to AAV
Blood·2012· 5 cited
Tregitope applications to tolerance induction in autoimmune diseases. (116.10)
The Journal of Immunology·2012
Cardiac Gene Transfer of Short Hairpin RNA Directed Against Phospholamban Effectively Knocks Down Gene Expression but Causes Cellular Toxicity in Canines
Human Gene Therapy·2011· 52 citedOpen Access
page 1 of 3Next →

Frequent Co-authors

Katherine A. High(32), Federico Mingozzi(21), Etiena Basner‐Tschakarjan(11), Shangzhen Zhou(10), Denise E. Sabatino(8), Federico Mingozzi(8), J. Fraser Wright(7), Valder R. Arruda(7), Margaret V. Ragni(6), Marcela V. Maus(6), Yifeng Chen(6), Gary C. Pien(6), George Buchlis(6), Xavier M. Anguela(5), Shyrie Edmonson(5), Jonathan D. Finn(5), Anne S. De Groot(5), Samuel L. Murphy(4), Hildegund C.J. Ertl(4), Ganes C. Sen(4)