Jonathan D. Finn

Oxford University Press (United Kingdom) — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

21h-index3.4kcitations60works2.52yr avg
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Research Topics

Virus-based gene therapy research(31), RNA Interference and Gene Delivery(16), CRISPR and Genetic Engineering(12), CAR-T cell therapy research(11), Hemophilia Treatment and Research(8)

Publications60 total

Designing AI-programmable therapeutics with the EDEN family of foundation models
2026Open Access
Highly Efficient Multiplexed Genome Engineering and Clone Selection to Enable Next Generation Induced Pluripotent Stem Cell (iPSC)-based Cell Therapies
2025Open Access
Ligase-mediated programmable genomic integration (L-PGI)
Nature Communications·2025Open Access
T-PGI: an engineered STITCHR system for scarless, programmable genome integration
2025Open Access
Development of circular AAV cargos for targeted seamless insertion with large serine integrases
Molecular Therapy — Methods & Clinical Development·2025· 3 citedOpen Access
Low RT-based Genome Editing Fidelity in Mouse Hepatocytes: Challenges and Solutions
2024· 1 citedOpen Access
Breaking Free: Development of Circular AAV Cargos for Targeted Seamless Integration in the Liver
2024Open Access
Engineered Bxb1 variants improve integrase activity and fidelity
2024· 3 citedOpen Access
Curative levels of endogenous gene replacement achieved in non-human primate liver using programmable genomic integration
2024· 5 citedOpen Access
Large Serine Integrase Off-Target Discovery with Deep Learning for Genome Wide Prediction
2024Open Access
Ligase-mediated programmable genomic integration (L-PGI): an efficient site-specific gene editing system that overcomes the limitations of reverse transcriptase-based editing systems
2024· 5 citedOpen Access
Unlocking the potential of iPSC-derived immune cells: engineering iNK and iT cells for cutting-edge immunotherapy
Frontiers in Immunology·2024· 11 citedOpen Access
Large Serine Integrase Off-target Discovery and Validation for Therapeutic Genome Editing
2024· 5 citedOpen Access
Therapeutic extracellular vesicle production is substantially increased by inhibition of cellular cholesterol biosynthesis
Biotechnology and Bioengineering·2023· 5 citedOpen Access
Diagnosis and treatment outcomes from prebronchodilator spirometry performed alongside lung cancer screening in a Lung Health Check programme
Thorax·2023· 6 citedOpen Access
Transfection reagent artefact likely accounts for some reports of extracellular vesicle function
Journal of Extracellular Vesicles·2022· 21 citedOpen Access
Identification Made Visible:
Penn State University Press eBooks·2021
Evolutionary insights into coagulation factor IX Padua and other high-specific-activity variants
Blood Advances·2021· 29 citedOpen Access
A versatile platform for generating engineered extracellular vesicles with defined therapeutic properties
Molecular Therapy·2021· 290 citedOpen Access
703 Engineered exosomes with altered cellular tropism achieve targeted STING agonist delivery and single-agent tumor control in vivo
Regular and Young Investigator Award Abstracts·2020· 1 citedOpen Access
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Frequent Co-authors

Valder R. Arruda(14), Shangzhen Zhou(11), Katherine A. High(10), Federico Mingozzi(6), Daniel J. Hui(5), Timothy C. Nichols(5), Brett Estes(5), Jenny Xie(5), Jesse C. Cochrane(5), Gary C. Pien(4), Etiena Basner‐Tschakarjan(4), Patrícia Favaro(4), Niels Broekstra(4), Paul P. Tak(4), Margriet J. Vervoordeldonk(4), Maike Thamsen Dunyak(4), Angela X. Nan(4), Madeleine R. Youniss(3), Paolo Simioni(3), Russell E. McConnell(3)