Jimmy de Melo

Penn Presbyterian Medical Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

19h-index1.1kcitations24works0.02yr avg
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Research Topics

Retinal Development and Disorders(16), Developmental Biology and Gene Regulation(7), Neurogenesis and neuroplasticity mechanisms(5), Zebrafish Biomedical Research Applications(4), Cell Adhesion Molecules Research(3)

Publications24 total

Amelioration of Neurosensory Structure and Function in Animal and Cellular Models of a Congenital Blindness
Molecular Therapy·2018· 26 citedOpen Access
A toolbox of immunoprecipitation-grade monoclonal antibodies to human transcription factors
Nature Methods·2018· 70 citedOpen Access
Ldb1 and Rnf12-dependent regulation of Lhx2 controls the relative balance between neurogenesis and gliogenesis in retina
Development·2018· 33 citedOpen Access
In Vivo Electroporation of Developing Mouse Retina
Methods in molecular biology·2017· 44 citedOpen Access
Ldb1 and Rnf12-dependent regulation of Lhx2 controls the relative balance between neurogenesis and gliogenesis in retina
2017· 9 citedOpen Access
A toolbox of immunoprecipitation-grade monoclonal antibodies against human transcription factors
2017Open Access
Regulation of <i>Brn</i>3b by <i>Dlx</i>1 and <i>Dlx</i>2 is required for retinal ganglion cell differentiation in the vertebrate retina
Development·2017· 32 citedOpen Access
The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis
Development·2016· 34 citedOpen Access
Control of lens development by Lhx2-regulated neuroretinal FGFs
Development·2016· 24 citedOpen Access
Multiple intrinsic factors act in concert with Lhx2 to direct retinal gliogenesis
Scientific Reports·2016· 42 citedOpen Access
Lhx2 Is an Essential Factor for Retinal Gliogenesis and Notch Signaling
Journal of Neuroscience·2016· 108 citedOpen Access
Control of lens fiber development by Lhx2-regulated neuroretinal Fgfs
Investigative Ophthalmology & Visual Science·2015
The LIM Homeodomain Factor Lhx2 Is Required for Hypothalamic Tanycyte Specification and Differentiation
Journal of Neuroscience·2014· 74 citedOpen Access
LHX2 Is Necessary for the Maintenance of Optic Identity and for the Progression of Optic Morphogenesis
Journal of Neuroscience·2013· 91 citedOpen Access
ISDN2012_0199: Lhx2 is required for the specification and differentiation of retinal Müller glia while also promoting formation of wide‐field amacrine cells
International Journal of Developmental Neuroscience·2012
Injury-independent induction of reactive gliosis in retina by loss of function of the LIM homeodomain transcription factor Lhx2
Proceedings of the National Academy of Sciences·2012· 112 citedOpen Access
&lt;em&gt;In vivo&lt;/em&gt; Electroporation of Developing Mouse Retina
Journal of Visualized Experiments·2011· 32 cited
&lt;em&gt;In vivo&lt;/em&gt; Electroporation of Developing Mouse Retina
Journal of Visualized Experiments·2011· 1 cited
The Spalt family transcription factor Sall3 regulates the development of cone photoreceptors and retinal horizontal interneurons
Development·2011· 69 citedOpen Access
The orphan nuclear hormone receptor <i>ERR</i> β controls rod photoreceptor survival
Proceedings of the National Academy of Sciences·2010· 80 cited
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Frequent Co-authors

Seth Blackshaw(18), Cristina Zibetti(7), Brian S. Clark(7), David D. Eisenstat(4), Anand Venkataraman(4), Thuzar Thein(3), Sooyeon Yoo(3), Guoyan Du(2), Ana L. Miranda‐Angulo(2), Guang-Hua Peng(2), Daniel A. Lee(2), Shiming Chen(2), Mario Fonseca(2), Kun Yang(2), José Irizarry(2), Mark Mackiewicz(2), Paolo Mita(2), Zheng Kuang(2), Xue Lin(2), D. Ghosh(2)