Setsuko Fujita‐Becker

Heidelberg University — Germany

Medicine · Health Sciences

14h-index1.0kcitations26works0.02yr avg
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Research Topics

Cardiomyopathy and Myosin Studies(23), Cellular Mechanics and Interactions(16), Muscle Physiology and Disorders(13), Force Microscopy Techniques and Applications(6), Cardiovascular Effects of Exercise(4)

Publications26 total

Inhibition of Arp2/3 Complex after ADP-Ribosylation of Arp2 by Binary Clostridioides Toxins
Cells·2022· 8 citedOpen Access
Functional Characterization of Cardiac Actin Mutants Causing Hypertrophic (p.A295S) and Dilated Cardiomyopathy (p.R312H and p.E361G)
International Journal of Molecular Sciences·2022· 5 citedOpen Access
De Novo Missense Mutations in TNNC1 and TNNI3 Causing Severe Infantile Cardiomyopathy Affect Myofilament Structure and Function and Are Modulated by Troponin Targeting Agents
International Journal of Molecular Sciences·2021· 17 citedOpen Access
Functional Characterization of Cardiac Actin Mutants Causing Hypertrophic (p.A295S) and Dilative Cardiomyopathy (p.R312H and p.E361G)
2021Open Access
Infantile restrictive cardiomyopathy: cTnI-R170G/W impair the interplay of sarcomeric proteins and the integrity of thin filaments
PLoS ONE·2020· 25 citedOpen Access
Interaction of isolated cross‐linked short actin oligomers with the skeletal muscle myosin motor domain
FEBS Journal·2018· 10 citedOpen Access
Force-producing ADP state of myosin bound to actin
Proceedings of the National Academy of Sciences·2016· 86 citedOpen Access
The Force Producing ADP State of Myosin Bound to Actin
Biophysical Journal·2016· 2 citedOpen Access
Structural Basis for the Allosteric Interference of Myosin Function by Reactive Thiol Region Mutations G680A and G680V
Journal of Biological Chemistry·2011· 18 citedOpen Access
Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2
2010
Mechanism, Regulation, and Functional Properties of Dictyostelium Myosin-1B
Journal of Biological Chemistry·2007· 28 citedOpen Access
Functional Characterization of the N-terminal Region of Myosin-2
Journal of Biological Chemistry·2006· 38 citedOpen Access
The actin-binding cleft: functional characterisation of myosin II with a strut mutation
Journal of Muscle Research and Cell Motility·2006· 13 cited
<i>Dictyostelium</i>myosin-IE is a fast molecular motor involved in phagocytosis
Journal of Cell Science·2006· 54 cited
Changes in Mg2+ Ion Concentration and Heavy Chain Phosphorylation Regulate the Motor Activity of a Class I Myosin
Journal of Biological Chemistry·2004· 59 citedOpen Access
Molecular engineering of a backwards-moving myosin motor
Nature·2004· 111 cited
Mutations in the relay loop region result in dominant‐negative inhibition of myosin II function in <i>Dictyostelium</i>
EMBO Reports·2002Open Access
Mutations in the relay loop region result in dominant‐negative inhibition of myosin II function in <i>Dictyostelium</i>
EMBO Reports·2002· 51 citedOpen Access
Viscous force in cardiac myofibrils is caused by actin-PEVK- titin interaction
Max Planck Institute for Plasma Physics·2002
PEVK Domain of Titin: An Entropic Spring with Actin-Binding Properties
Journal of Structural Biology·2002· 202 cited
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Frequent Co-authors

Dietmar J. Manstein(15), Michael A. Geeves(10), Rasmus R. Schröder(7), Georgios Tsiavaliaris(6), Hans Georg Mannherz(6), Andreas Mügge(4), Kornélia Jaquet(4), Wolfgang A. Linke(3), Michael Kulke(3), Ciprian Neagoe(3), Mathias Gautel(3), Marcus Furch(3), Kenneth C. Holmes(3), Ulrike Dürrwang(3), Roua Hassoun(3), Sarah F. Wulf(2), Virginie Ropars(2), Marco Oster(2), G. Hofhaus(2), Leonardo G. Trabuco(2)