Leonard Schmiester

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index691citations47works0.22yr avg
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Research Topics

Gene Regulatory Network Analysis(19), Advanced Breast Cancer Therapies(9), Protein Structure and Dynamics(7), Breast Cancer Treatment Studies(7), Bioinformatics and Genomic Networks(6)

Publications47 total

pyPESTO - Parameter EStimation TOolbox for python
Zenodo (CERN European Organization for Nuclear Research)·2026Open Access
pyPESTO - Parameter EStimation TOolbox for python
Zenodo (CERN European Organization for Nuclear Research)·2025Open Access
Data from Computational Model Predicts Patient Outcomes in Luminal B Breast Cancer Treated with Endocrine Therapy and CDK4/6 Inhibition
2024Open Access
Supplementary Information 1 from Computational Model Predicts Patient Outcomes in Luminal B Breast Cancer Treated with Endocrine Therapy and CDK4/6 Inhibition
2024Open Access
Data from Computational Model Predicts Patient Outcomes in Luminal B Breast Cancer Treated with Endocrine Therapy and CDK4/6 Inhibition
2024Open Access
Supplementary Information 1 from Computational Model Predicts Patient Outcomes in Luminal B Breast Cancer Treated with Endocrine Therapy and CDK4/6 Inhibition
2024Open Access
Supplementary Figures 1 from Computational Model Predicts Patient Outcomes in Luminal B Breast Cancer Treated with Endocrine Therapy and CDK4/6 Inhibition
2024Open Access
Supplementary Figures 1 from Computational Model Predicts Patient Outcomes in Luminal B Breast Cancer Treated with Endocrine Therapy and CDK4/6 Inhibition
2024Open Access
Computational Model Predicts Patient Outcomes in Luminal B Breast Cancer Treated with Endocrine Therapy and CDK4/6 Inhibition
Clinical Cancer Research·2024· 3 citedOpen Access
Abstract PO4-02-01: Characterization of immune and malignant cell evolution upon treatment pressure with aromatase inhibitors in locally advanced estrogen positive breast cancer
Cancer Research·2024
Abstract PO4-14-09: A computational model of the mechanisms of action of combined endocrine therapy and CDK4/6 inhibition predicts outcome in patients with Luminal B breast cancer
Cancer Research·2024
Abstract PO3-23-08: Cancer and immune cells evolutionary trajectories under treatment with the aromatase inhibitor letrozole and the CDK4/6 inhibitor ribociclib
Cancer Research·2024
Abstract LB394: Tumor evolution upon treatment pressure with aromatase inhibitors in locally advanced estrogen receptor positive breast cancer
Cancer Research·2024
pyPESTO: a modular and scalable tool for parameter estimation for dynamic models
Bioinformatics·2023· 48 citedOpen Access
pyPESTO: A modular and scalable tool for parameter estimation for dynamic models
arXiv (Cornell University)·2023· 3 citedOpen Access
Phenotypic deconvolution in heterogeneous cancer cell populations using drug-screening data
Cell Reports Methods·2023· 11 citedOpen Access
Phenotypic deconvolution in heterogeneous cancer cell populations using drug screening data
2022· 1 citedOpen Access
Mini-batch optimization enables training of ODE models on large-scale datasets
Nature Communications·2022· 25 citedOpen Access
COVID‐19 Disease Map, a computational knowledge repository of virus‐host interaction mechanisms
Molecular Systems Biology·2021Open Access
COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms
Molecular Systems Biology·2021· 107 citedOpen Access
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Frequent Co-authors

Jan Hasenauer(27), Daniel Weindl(20), Paul Stapor(16), Yannik Schälte(13), Arnoldo Frigessi(13), Vessela N. Kristensen(11), Fabian Fröhlich(10), Alvaro Köhn‐Luque(10), Xavier Tekpli(10), Jürgen Geisler(9), Jakob Vanhoefer(8), Philipp Städter(8), Fara Brasó‐Maristany(8), Aleix Prat(8), Christoph Wierling(7), Bodo Lange(7), Blanca González‐Farré(7), Tomás Pascual(7), Joaquín Gavilá(7), Simon Merkt(6)