Lin Tai

Walter and Eliza Hall Institute of Medical Research — Australia

Medicine · Health Sciences

20h-index2.6kcitations212works0.02yr avg
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Research Topics

Cancer-related Molecular Pathways(163), Cancer Genomics and Diagnostics(19), CAR-T cell therapy research(14), Cell death mechanisms and regulation(13), CRISPR and Genetic Engineering(12)

Publications212 total

3107 – ADVANCED CRISPR KNOCKOUT AND ACTIVATION MOUSE MODELS AS TOOLS FOR INVESTIGATING HEMATOLOGY AND HEMATOLOGICAL MALIGNANCIES
Experimental Hematology·2025
Genome-wide in vivo CRISPR screens identify GATOR1 complex as a tumor suppressor in Myc-driven lymphoma
Nature Communications·2025· 1 citedOpen Access
A novel, high-density CRISPR activation platform for mapping cancer dependencies and resistance pathways <i>ex vivo</i> and <i>in vivo</i>
2025Open Access
Transcriptomic changes including p53 dysregulation prime DNMT3A mutant cells for transformation
EMBO Reports·2025· 1 citedOpen Access
Advancing the genetic engineering toolbox by combining AsCas12a knock-in mice with ultra-compact screening
Nature Communications·2025· 3 citedOpen Access
Mouse models to investigate in situ cell fate decisions induced by p53
The EMBO Journal·2024· 2 citedOpen Access
Transcriptomic alterations including p53 pathway dysregulation prime DNMT3A mutant cells for transformation
2024Open Access
Advancing the genetic engineering toolbox by combining <i>AsCas12a</i> knock-in mice with ultra-compact screening
2024· 1 citedOpen Access
Supplementary Data Table S9 from Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells
2024Open Access
Supplementary Data Figure S5 from Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells
2024Open Access
Supplementary Data Figure S7 from Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells
2024Open Access
Supplementary Data Figure S7 from Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells
2024Open Access
Supplementary Data Figure S27 from Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells
2024Open Access
Supplementary Data Table S8 from Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells
2024Open Access
Supplementary Data Figure S27 from Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells
2024Open Access
Supplementary Data Table S5 from Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells
2024Open Access
Supplementary Data Figure S16 from Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells
2024Open Access
Supplementary Data Table S6 from Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells
2024Open Access
Supplementary Data Figure S2 from Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells
2024Open Access
Supplementary Data Figure S15 from Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells
2024Open Access
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Frequent Co-authors

Andreas Strasser(40), Marco J. Herold(39), Gemma L. Kelly(21), Andrew J. Kueh(19), Sarah T. Diepstraten(17), David C.S. Huang(15), Catherine Chang(13), Alexandra L. Garnham(12), Deeksha Kaloni(12), Connie S.N. Li Wai Suen(11), Jane E. Visvader(11), Elizabeth Lieschke(10), Stephen Wilcox(9), Chris Riffkin(9), Allan Shuai Huang(9), Zilu Wang(8), Matteo Burigotto(8), Sabrina Ghetti(8), François Vaillant(8), Tao Tan(8)