Juliette Hordeaux

Integrated BioTherapeutics (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index1.8kcitations46works9.92yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Virus-based gene therapy research(17), Lysosomal Storage Disorders Research(16), Genetic Neurodegenerative Diseases(5), Veterinary Oncology Research(5), Mitochondrial Function and Pathology(4)

Publications46 total

Deciphering the role and contribution of AAV immune responses to DRG toxicity
Molecular Therapy Advances·2026Open Access
Advancing AAV technology—From promise to product
Molecular Therapy Advances·2026Open Access
Abstract 4366785: Efficacy and Safety of a Novel AAV <i>FXN</i> Gene Therapy (SGT-212) for the Treatment of Friedreich’s Ataxia
Circulation·2025
Lung endothelial transduction in a patient that succumbed to acute respiratory distress syndrome following high-dose rAAV9 gene therapy
Molecular Therapy·2025· 5 cited
Functional Characterization of Parallel Fiber-Purkinje Cell Synapses in Two Friedreich’s Ataxia Mouse Models
The Cerebellum·2025· 2 citedOpen Access
Neuropathological Findings in Nonclinical Species Following Administration of Adeno-Associated Virus (AAV)-Based Gene Therapy Vectors
Toxicologic Pathology·2024· 7 cited
High-dose systemic adeno-associated virus vector administration causes liver and sinusoidal endothelial cell injury
Molecular Therapy·2024· 55 citedOpen Access
Quantification of human mature frataxin protein expression in nonhuman primate hearts after gene therapy
Communications Biology·2023· 6 citedOpen Access
Positron Emission Tomography Quantitative Assessment of Off-Target Whole-Body Biodistribution of I-124-Labeled Adeno-Associated Virus Capsids Administered to Cerebral Spinal Fluid
Human Gene Therapy·2023· 10 citedOpen Access
Quantification of human mature frataxin protein expression in nonhuman primate hearts after gene therapy
Research Square (Research Square)·2023Open Access
Immune transgene-dependent myocarditis in macaques after systemic administration of adeno-associated virus expressing human acid alpha-glucosidase
Frontiers in Immunology·2023· 18 citedOpen Access
Efficacy and Safety of a Krabbe Disease Gene Therapy
Human Gene Therapy·2022· 48 citedOpen Access
Development of a novel gene therapy for Fabry disease: Engineered alpha-galactosidase A transgene for improved stability
Molecular Genetics and Metabolism·2021
MicroRNA-mediated inhibition of transgene expression reduces dorsal root ganglion toxicity by AAV vectors in primates
Science Translational Medicine·2020· 159 cited
Adeno-Associated Virus-Induced Dorsal Root Ganglion Pathology
Human Gene Therapy·2020· 238 citedOpen Access
Intra-CSF AAV9 and AAVrh10 Administration in Nonhuman Primates: Promising Routes and Vectors for Which Neurological Diseases?
Molecular Therapy — Methods & Clinical Development·2020· 121 citedOpen Access
Randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared with etoposide phosphate, in dogs with naturally occurring lymphoma
Oncotarget·2020· 6 citedOpen Access
Untitled
Oncotarget·2020Open Access
Assessment of adeno-associated virus gene therapies efficacy on acid alpha-glucosidase restoration and glycogenstorage correction in cardiac muscle of Pompe disease mice using synchrotron infrared and ultravioletmicrospectroscopies
Journal of Spectral Imaging·2019· 1 citedOpen Access
Safe and Sustained Expression of Human Iduronidase After Intrathecal Administration of Adeno-Associated Virus Serotype 9 in Infant Rhesus Monkeys
Human Gene Therapy·2019· 75 citedOpen Access
page 1 of 3Next →

Frequent Co-authors

James M. Wilson(17), Johan Deniaud(14), Marie-Anne Colle(12), Laurence Dubreil(11), Elizabeth L. Buza(10), Peter Bell(10), Christian Hinderer(9), Nathan Katz(5), Tamara Goode(5), Jessica A. Chichester(5), Quentin Pascal(5), Frédéric Jamme(5), Cecilia Dyer(4), Gourav Roy Choudhury(4), Chunjuan Song(4), Karim Bey(4), Carine Ciron(4), Marion Fusellier(4), Lydie Lagalice(4), Mireille Ledevin(4)