Peter Bell

Integrated BioTherapeutics (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

51h-index8.1kcitations120works5.02yr avg
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Research Topics

Virus-based gene therapy research(87), RNA Interference and Gene Delivery(29), CRISPR and Genetic Engineering(27), Viral gastroenteritis research and epidemiology(16), Viral Infections and Immunology Research(15)

Publications120 total

Lung endothelial transduction in a patient that succumbed to acute respiratory distress syndrome following high-dose rAAV9 gene therapy
Molecular Therapy·2025· 5 cited
Lipid Nanoparticle mRNA Therapy Improves Survival and Reduces Serum Branched-Chain Amino Acids in Mouse Models of Maple Syrup Urine Disease
Human Gene Therapy·2024· 5 cited
Integrated vector genomes may contribute to long-term expression in primate liver after AAV administration
Nature Biotechnology·2023· 119 citedOpen Access
Vector Affinity and Receptor Distribution Define Tissue-Specific Targeting in an Engineered AAV Capsid
Journal of Virology·2023· 13 citedOpen Access
Immune transgene-dependent myocarditis in macaques after systemic administration of adeno-associated virus expressing human acid alpha-glucosidase
Frontiers in Immunology·2023· 18 citedOpen Access
Neonatal Fc Receptor Inhibition Enables Adeno-Associated Virus Gene Therapy Despite Pre-Existing Humoral Immunity
Human Gene Therapy·2023· 16 cited
Treating Transthyretin Amyloidosis via Adeno-Associated Virus Vector Delivery of Meganucleases
Human Gene Therapy·2022· 5 citedOpen Access
Intravenous immunoglobulin prevents peripheral liver transduction of intrathecally delivered AAV vectors
Molecular Therapy — Methods & Clinical Development·2022· 8 citedOpen Access
Loss of transgene expression limits liver gene therapy in primates
2022· 10 citedOpen Access
Prednisolone reduces the interferon response to AAV in cynomolgus macaques and may increase liver gene expression
Molecular Therapy — Methods & Clinical Development·2022· 22 citedOpen Access
Developing a second-generation clinical candidate AAV vector for gene therapy of familial hypercholesterolemia
Molecular Therapy — Methods & Clinical Development·2021· 23 citedOpen Access
Long-term stable reduction of low-density lipoprotein in nonhuman primates following in vivo genome editing of PCSK9
Molecular Therapy·2021· 55 citedOpen Access
Development of a novel gene therapy for Fabry disease: Engineered alpha-galactosidase A transgene for improved stability
Molecular Genetics and Metabolism·2021
MicroRNA-mediated inhibition of transgene expression reduces dorsal root ganglion toxicity by AAV vectors in primates
Science Translational Medicine·2020· 159 cited
Adeno‐associated virus serotype 1‐based gene therapy for FTD caused by <i>GRN</i> mutations
Annals of Clinical and Translational Neurology·2020· 51 citedOpen Access
Translational Feasibility of Lumbar Puncture for Intrathecal AAV Administration
Molecular Therapy — Methods & Clinical Development·2020· 66 citedOpen Access
A mutation-independent CRISPR-Cas9–mediated gene targeting approach to treat a murine model of ornithine transcarbamylase deficiency
Science Advances·2020· 65 citedOpen Access
Safe and Sustained Expression of Human Iduronidase After Intrathecal Administration of Adeno-Associated Virus Serotype 9 in Infant Rhesus Monkeys
Human Gene Therapy·2019· 75 citedOpen Access
The GPI-Linked Protein LY6A Drives AAV-PHP.B Transport across the Blood-Brain Barrier
Molecular Therapy·2019· 218 citedOpen Access
A Gene Therapy Approach to Improve Copper Metabolism and Prevent Liver Damage in a Mouse Model of Wilson Disease
Human Gene Therapy Clinical Development·2019· 23 cited
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Frequent Co-authors

James M. Wilson(49), Lili Wang(19), Roberto Calcedo(15), Christian Hinderer(11), Luk H. Vandenberghe(10), Guangping Gao(10), Elizabeth L. Buza(9), Hongwei Yu(9), Yanqing Zhu(9), Rebecca Grant(9), Tamara Goode(6), Zhenning He(6), Mark L. Batshaw(6), Juliette Hordeaux(6), Nathan Katz(5), Hiroki Morizono(5), Julio Sanmiguel(5), Nelson A. Wivel(5), Mark E. Haskins(5), Laura K. Richman(4)