Alexandra Maria Psaras

Binghamton University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

6h-index100citations15works0.52yr avg
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Research Topics

Advanced biosensing and bioanalysis techniques(8), DNA and Nucleic Acid Chemistry(7), RNA Interference and Gene Delivery(7), Hedgehog Signaling Pathway Studies(3), Epigenetics and DNA Methylation(2)

Publications15 total

Ovarian Cancer Susceptibility and Chemosensitivity to KRAS Modulation
International Journal of Molecular Sciences·2026Open Access
Resin-Supported Site-Specific Antibody Conjugation Method Leads to Antibody-Drug Conjugates with Retained Efficacy and Improved Stability
Bioconjugate Chemistry·2025· 1 citedOpen Access
Targeting MYC Regulation with Polypurine Reverse Hoogsteen Oligonucleotides
International Journal of Molecular Sciences·2022· 9 citedOpen Access
A cell-based bioluminescence reporter assay of human Sonic Hedgehog protein autoprocessing to identify inhibitors and activators
Journal of Biological Chemistry·2022· 2 citedOpen Access
RYBP Sensitizes Cancer Cells to PARP Inhibitors by Regulating ATM Activity
International Journal of Molecular Sciences·2022· 6 citedOpen Access
Indoloquinoline-Mediated Targeted Downregulation of KRAS through Selective Stabilization of the Mid-Promoter G-Quadruplex Structure
Genes·2022· 7 citedOpen Access
Bioluminescence-based reporters for characterizing inhibitors and activators of human Sonic Hedgehog protein autoprocessing in live cells at high throughput
2022Open Access
Abstract 675: Facilitating G-quadruplex formation in the KRAS promoter with polypurine reverse Hoogsteen oligonucleotides
Cancer Research·2022
Optimization of DOTAP/chol Cationic Lipid Nanoparticles for mRNA, pDNA, and Oligonucleotide Delivery
AAPS PharmSciTech·2022· 56 citedOpen Access
Targeting KRAS Regulation with PolyPurine Reverse Hoogsteen Oligonucleotides
International Journal of Molecular Sciences·2022· 9 citedOpen Access
Targeted Downregulation of MYC through G-quadruplex Stabilization by DNAi
Molecules·2021· 4 citedOpen Access
Abstract 1246: Anticancer activitiy of indolo[2,3-c]quinoline stabilization of the KRAS promoter G4mid structure
Cancer Research·2021
Abstract 653: Enhancing therapies for MYC-overexpressing Non-Hodgkin's lymphoma: A role for MYC downregulation and new combination therapies
Cancer Research·2020
Improved Sonic Hedgehog Protein Autoprocessing Assay in Cells Using Luciferase Reporter System
The FASEB Journal·2020
G-quadruplex deconvolution with physiological mimicry enhances primary screening: Optimizing the FRET Melt2 assay
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms·2019· 6 citedOpen Access

Frequent Co-authors

Tracy A. Brooks(12), Simonas Valiuska(3), Verónique Noé(3), Carlos J. Ciudad(3), L. Nathan Tumey(3), Daniel A. Ciulla(3), Rebecca Mancusi(3), Brian P. Callahan(3), Jared T. Miller(2), Patricia Dranchak(2), John L. Pezzullo(2), Ganesha Rai(2), José‐Luis Giner(2), James Inglese(2), Mengwei Sun(1), Utkarsh J. Dang(1), Yuhao Yuan(1), Ositomiwa O. Osipitan(1), Fake Lu(1), Anthony J. Di Pasqua(1)