Yosef Shiloh

Tel Aviv University — Israel

Biochemistry, Genetics and Molecular Biology · Life Sciences

74h-index33.7kcitations251works5.32yr avg
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Research Topics

DNA Repair Mechanisms(165), Cancer-related Molecular Pathways(66), Carcinogens and Genotoxicity Assessment(62), Mitochondrial Function and Pathology(27), Genetic Neurodegenerative Diseases(26)

Publications250 total

287P ILF2 and UBQLN4 gene amplifications are prognostic factors of disease outcome in intrahepatic cholangiocarcinoma
Annals of Oncology·2025
ZC3H4 safeguards genome integrity by preventing transcription-replication conflicts at noncoding RNA loci
Science Advances·2025· 1 citedOpen Access
Re-epithelialization of cancer cells increases autophagy and DNA damage: Implications for breast cancer dormancy and relapse
Science Signaling·2025· 2 cited
Inducible re-epithelialization of cancer cells increases autophagy and DNA damage: implications for breast cancer dormancy
2025Open Access
The cGAS–STING, p38 MAPK, and p53 pathways link genome instability to accelerated cellular senescence in ATM-deficient murine lung fibroblasts
Proceedings of the National Academy of Sciences·2025· 9 citedOpen Access
Broad repression of DNA repair genes in senescent cells identified by integration of transcriptomic data
Nucleic Acids Research·2024· 7 citedOpen Access
Visualizing the DNA Damage Response in Purkinje Cells Using Cerebellar Organotypic Cultures
Journal of Visualized Experiments·2024
<i>ATM</i> germ line pathogenic variants affect outcomes in children with ataxia-telangiectasia and hematological malignancies
Blood·2024· 23 citedOpen Access
<i>ATM</i> Germline Pathogenic Variants Affect Treatment Outcomes in Children with Acute Lymphoblastic Leukemia/Lymphoma and Ataxia Telangiectasia
Blood·2023· 5 cited
Accelerated replicative senescence of ataxia‐telangiectasia skin fibroblasts is retained at physiologic oxygen levels, with unique and common transcriptional patterns
Aging Cell·2023· 10 citedOpen Access
Ataxia Telangiectasia Mutated Signaling Delays Skin Pigmentation upon UV Exposure by Mediating MITF Function toward DNA Repair Mode
Journal of Investigative Dermatology·2023· 5 citedOpen Access
Genomic Amplification of UBQLN4 Is a Prognostic and Treatment Resistance Factor
Cells·2022· 4 citedOpen Access
New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary
Aging·2022· 289 citedOpen Access
UBQLN4 promotes STING proteasomal degradation during cisplatin‐induced DNA damage in triple‐negative breast cancer
Clinical and Translational Medicine·2022· 14 citedOpen Access
The hallmarks of aging in Ataxia-Telangiectasia
Ageing Research Reviews·2022· 39 citedOpen Access
Abstract P4-01-11: UBQLN4 regulates cisplatin-resistance in triple-negative breast cancer by targeting BAT3 for proteasomal degradation
Cancer Research·2022
Abstract LB218: MRE11A expression regulated by UBQLN4 is related to cisplatin-resistance and survival in patients with esophageal squamous cell carcinoma
Cancer Research·2021
Regulation of MRE11A by UBQLN4 leads to cisplatin resistance in patients with esophageal squamous cell carcinoma
Molecular Oncology·2021· 21 citedOpen Access
It takes three to the DNA damage response tango
Molecular & Cellular Oncology·2021· 8 citedOpen Access
Faculty Opinions recommendation of Repeat expansions confer WRN dependence in microsatellite-unstable cancers.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2020
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Frequent Co-authors

Yael Ziv(13), Galit Rotman(8), Danilo A. Tagle(5), Francis S. Collins(5), Ran Elkon(5), Yaniv Lerenthal(4), Anat Bar‐Shira(4), Richard A. Gatti(4), Martin F. Lavin(4), Lilach Moyal(4), Dganit Shkedy(4), Michael B. Kastan(4), Moshe Oren(4), David J. Chen(4), Kinneret Savitsky(3), Luciana Chessa(3), Ze’ev A. Ronai(3), Shih-Ya Wang(3), Ron Shamir(3), Chaim Linhart(3)