Dganit Shkedy

Tel Aviv University — Israel

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index2.1kcitations14works0.02yr avg
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Research Topics

DNA Repair Mechanisms(9), Cancer-related Molecular Pathways(6), Ubiquitin and proteasome pathways(4), Cancer Research and Treatments(4), Mitochondrial Function and Pathology(3)

Publications14 total

Regulation of Elg1 activity by phosphorylation
Cell Cycle·2015· 15 citedOpen Access
Requirement of ATM-Dependent Monoubiquitylation of Histone H2B for Timely Repair of DNA Double-Strand Breaks (vol 41, pg 529, 2011)
Max Planck Institute for Plasma Physics·2011· 12 cited
Requirement of ATM-Dependent Monoubiquitylation of Histone H2B for Timely Repair of DNA Double-Strand Breaks
Molecular Cell·2011· 21 citedOpen Access
Requirement of ATM-Dependent Monoubiquitylation of Histone H2B for Timely Repair of DNA Double-Strand Breaks
Molecular Cell·2011· 394 citedOpen Access
Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage
Proceedings of the National Academy of Sciences·2005· 179 citedOpen Access
ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage
Genes & Development·2001· 701 citedOpen Access
Ataxia-telangiectasia: chronic activation of damage-responsive functions is reduced by α-lipoic acid
Oncogene·2001· 68 cited
Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage
Proceedings of the National Academy of Sciences·1999· 450 citedOpen Access
Identification of ATM mutations using extended RT‐PCR and restriction endonuclease fingerprinting, and elucidation of the repertoire of A‐T mutations in Israel
Human Mutation·1998· 2 cited
Identification of ATM mutations using extended RT-PCR and restriction endonuclease fingerprinting, and elucidation of the repertoire of A-T mutations in Israel
Human Mutation·1998· 36 cited
On the involvement of calpains in the degradation of the tumor suppressor protein p53
FEBS Letters·1997· 85 citedOpen Access
Isolation, Characterization, and Partial Purification of a Novel Ubiquitin-Protein Ligase, E3
Journal of Biological Chemistry·1996· 38 citedOpen Access
Complete reconstitution of conjugation and subsequent degradation of the tumor suppressor protein p53 by purified components of the ubiquitin proteolytic system
FEBS Letters·1994· 40 citedOpen Access
Degradation of the tumor suppressor protein p53 by the ubiquitin-mediated proteolytic system requires a novel species of ubiquitin-carrier protein, E2
Journal of Biological Chemistry·1994· 102 citedOpen Access

Frequent Co-authors

Yosef Shiloh(8), Aaron Ciechanover(7), Moshe Oren(5), Rami Khosravi(3), Lilach Moyal(3), Yaniv Lerenthal(3), Mali Gana‐Weisz(3), Gilad Mass(3), Sairei So(3), Berina Eppink(3), Young‐Min Chung(3), Gil Shalev(3), Efrat Shema(3), Nechama I. Smorodinsky(3), Nicole van Vliet(3), Bernhard Küster(3), Matthias Mann(3), Jochen Dahm‐Daphi(3), Roland Kanaar(3), Beatrice Bercovich(3)