Fernando Rodrigues‐Lima

Centre National de la Recherche Scientifique — France

Biochemistry, Genetics and Molecular Biology · Life Sciences

37h-index3.9kcitations252works6.52yr avg
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Research Topics

Carcinogens and Genotoxicity Assessment(21), Polyamine Metabolism and Applications(21), Protein Tyrosine Phosphatases(15), Epigenetics and DNA Methylation(13), Carbon Nanotubes in Composites(12)

Publications252 total

Structural and functional characterization of CREB-binding protein (CREBBP) as a histone propionyltransferase
Journal of Biological Chemistry·2025Open Access
Molecular and cellular effects of hydroxy-1,4 naphthoquinones used in dermatological and cosmetic applications on human protein tyrosine phosphatase PTP1B in human keratinocytes
Molecular Pharmacology·2025· 1 cited
Blunted CD40-responsive enhancer activation in <i>CREBBP</i>-mutant lymphomas can be restored by enforced CD4 T-cell engagement
Blood·2025· 4 citedOpen Access
Loss of WNT2B Results in Epithelial Defects and Predisposes to Gastrointestinal Dysplasia in Humans
Cellular and Molecular Gastroenterology and Hepatology·2025· 1 citedOpen Access
Metabolic dysregulation in myelodysplastic neoplasm: impact on pathogenesis and potential therapeutic targets
Medical Oncology·2024· 1 citedOpen Access
Structure and function of the lysine methyltransferase SETD2 in cancer: From histones to cytoskeleton
Neoplasia·2024· 16 citedOpen Access
Haploinsufficiency in PTPN2 leads to early-onset systemic autoimmunity from Evans syndrome to lupus
The Journal of Experimental Medicine·2024· 25 citedOpen Access
Targeting neutrophil extracellular traps: A novel strategy in hematologic malignancies
Biomedicine & Pharmacotherapy·2024· 6 citedOpen Access
Vemurafenib induces senescence in acute myeloid leukemia and myelodysplastic syndrome by activating the HIPPO signaling pathway: implications for potential targeted therapy
Biology Direct·2024· 1 citedOpen Access
EGCG-like non-competitive inhibitor of DYRK1A rescues cognitive defect in a down syndrome model
European Journal of Medicinal Chemistry·2024· 10 citedOpen Access
Structural and enzymatic evidence for the methylation of the ACK1 tyrosine kinase by the histone lysine methyltransferase SETD2
Biochemical and Biophysical Research Communications·2023· 5 cited
U2AF1 in various neoplastic diseases and relevant targeted therapies for malignant cancers with complex mutations (Review)
Oncology Reports·2023· 11 citedOpen Access
Author Correction: CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder
Nature Communications·2023Open Access
CREBBP lysine acetyltransferase domain mutations create zombie enzymes that alter chromatin loading dynamics and prevent EP300 redundancy
2023· 1 citedOpen Access
Legionella para-effectors target chromatin and promote bacterial replication
Nature Communications·2023· 25 citedOpen Access
The Addiction-Susceptibility TaqIA/Ankk1 Controls Reward and Metabolism Through D2 Receptor-Expressing Neurons
Biological Psychiatry·2023· 19 citedOpen Access
Myelodysplastic Syndrome associated TET2 mutations affect NK cell function and genome methylation
Nature Communications·2023· 36 citedOpen Access
CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder
Nature Communications·2022· 19 citedOpen Access
Trifloxystrobin blocks the growth of Theileria parasites and is a promising drug to treat Buparvaquone resistance
Communications Biology·2022· 15 citedOpen Access
<i>Crebbp</i> Kat Domain Missense Mutations Alter Its Dynamic Loading Onto Chromatin and Create a Transcription Factor Sink
Blood·2022
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Frequent Co-authors

Jean‐Marie Dupret(26), Julien Dairou(17), Matilda Katan(7), Michelle B. Josephs(5), Edith Sim(5), Tom D. Bunney(4), Jérémy Berthelet(4), Patrick Vicart(4), Noureddine Atmane(4), Marta Martins(4), Salik Hussain(3), Romain Duval(3), Raymond Frade(3), Nathalie Janel(3), Bertrand Goudeau(3), B. Pluvinage(3), Armelle Baeza‐Squiban(2), Sonja Boland(2), Richard Harris(2), S. Mark Roe(2)