R. W. Dougherty

Agricultural and Biological Sciences · Life Sciences

26h-index2.4kcitations64works0.02yr avg
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Research Topics

Ruminant Nutrition and Digestive Physiology(7), Meat and Animal Product Quality(6), Neuropeptides and Animal Physiology(6), Receptor Mechanisms and Signaling(6), Neuroscience and Neuropharmacology Research(4)

Publications63 total

Novel KV7 ion channel openers for the treatment of epilepsy and implications for detrusor tissue contraction
Bioorganic & Medicinal Chemistry Letters·2018· 27 citedOpen Access
CCDC 1855751: Experimental Crystal Structure Determination
The Cambridge Structural Database·2018Open Access
Problems Associated with Feeding Farm Livestock under Intensive Systems1
World review of nutrition and dietetics·2015· 13 cited
Pharmacology of INS37217 [P1-(Uridine 5′)-P4- (2′-deoxycytidine 5′)tetraphosphate, Tetrasodium Salt], a Next-Generation P2Y2 Receptor Agonist for the Treatment of Cystic Fibrosis
Journal of Pharmacology and Experimental Therapeutics·2002· 149 cited
Synthesis and P2Y receptor activity of a series of uridine dinucleoside 5′-polyphosphates
Bioorganic & Medicinal Chemistry Letters·2001· 120 citedOpen Access
DRUG ANALYSIS BASED ON SIGNALING RESPONSES TO G-PROTEIN-COUPLED RECEPTORS
Journal of Receptors and Signal Transduction·2001· 8 cited
Drug Analysis Based
1998
Optimization of 3-(1<i>H</i>-Indazol-3-ylmethyl)-1,5-benzodiazepines as Potent, Orally Active CCK-A Agonists
Journal of Medicinal Chemistry·1997· 86 citedOpen Access
4-Substituted Uridine 5′-Triphosphates as Agonists of the P<sub>2Y2</sub>Purinergic Receptor
Nucleosides and Nucleotides·1997· 11 cited
ChemInform Abstract: Discovery of 1,5‐Benzodiazepines with Peripheral Cholecystokinin (CCK‐ A) Receptor Agonist Activity (II): Optimization of the C3 Amino Substituent.
ChemInform·1997
Detailed Characterization of a Purified Type 4 Phosphodiesterase, HSPDE4B2B: Differentiation of High- and Low-Affinity (R)-Rolipram Binding
Protein Expression and Purification·1997· 45 cited
ChemInform Abstract: 3‐(2‐(N‐Phenylacetamide))‐1,5‐benzodiazepines: Orally Active, Binding Selective CCK‐A Agonists.
ChemInform·1996
Relationship Between Native and Recombinant Cholecystokinin Receptors
Pancreas·1996· 104 cited
3-(1<i>H</i>-Indazol-3-ylmethyl)-1,5-benzodiazepines:  CCK-A Agonists That Demonstrate Oral Activity as Satiety Agents
Journal of Medicinal Chemistry·1996· 29 citedOpen Access
3-[2-(<i>N</i>-Phenylacetamide)]-1,5-benzodiazepines:  Orally Active, Binding Selective CCK-A Agonists
Journal of Medicinal Chemistry·1996· 23 citedOpen Access
Discovery of 1,5-Benzodiazepines with Peripheral Cholecystokinin (CCK-A) Receptor Agonist Activity. 1. Optimization of the Agonist “Trigger”
Journal of Medicinal Chemistry·1996· 101 citedOpen Access
Discovery of 1,5-Benzodiazepines with Peripheral Cholecystokinin (CCK-A) Receptor Agonist Activity (II):  Optimization of the C3 Amino Substituent
Journal of Medicinal Chemistry·1996· 37 citedOpen Access
Modification of Receptor Selectivity and Functional Activity in Cholecystokinin Peptoid Ligands
Journal of Medicinal Chemistry·1995· 16 citedOpen Access
Structure-activity relationships involving the catechol subunit of rolipram
Bioorganic & Medicinal Chemistry Letters·1994· 15 cited
Dynamics of the Diradylglycerol Responses of Stimulated Phagocytes
Journal of Biological Chemistry·1989· 58 citedOpen Access
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Frequent Co-authors

Dallas K. Croom(7), Michael K. James(7), Mary K. Grizzle(6), Michael F. Johnson(6), Elizabeth E. Sugg(6), Milton J. Allison(6), J E Niedel(5), Gregory N. Ervin(5), Kennedy L. Queen(5), Larry S. Birkemo(4), Brad R. Henke(4), Timothy M. Willson(4), R. E. Hungate(3), Benjamin R. Yerxa(3), Christopher Aquino(3), Milana Dezube(3), Gavin C. Hirst(3), W.F. Shipe(3), Rayomand J. Unwalla(3), J. A. Bucklin(3)