Sandlin P. Seguin

University of Pittsburgh — United States

Medicine · Health Sciences

8h-index440citations10works0.02yr avg
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Research Topics

Polyomavirus and related diseases(5), Antenna Design and Analysis(3), Heat shock proteins research(3), Full-Duplex Wireless Communications(3), Protein Structure and Dynamics(1)

Publications10 total

Synthesis and structure–activity relationships of small molecule inhibitors of the simian virus 40 T antigen oncoprotein, an anti-polyomaviral target
Bioorganic & Medicinal Chemistry·2014· 8 cited
Ciprofloxacin is an inhibitor of the Mcm2-7 replicative helicase
Bioscience Reports·2013· 51 citedOpen Access
Table of Contents
Biological Psychiatry·2013Open Access
Allosteric Heat Shock Protein 70 Inhibitors Rapidly Rescue Synaptic Plasticity Deficits by Reducing Aberrant Tau
Biological Psychiatry·2013· 105 citedOpen Access
Synthesis and Initial Evaluation of YM-08, a Blood-Brain Barrier Permeable Derivative of the Heat Shock Protein 70 (Hsp70) Inhibitor MKT-077, Which Reduces Tau Levels
ACS Chemical Neuroscience·2013· 127 citedOpen Access
A screen for modulators of large T antigen’s ATPase activity uncovers novel inhibitors of Simian Virus 40 and BK virus replication
Antiviral Research·2012· 20 citedOpen Access
Identification of small molecule inhibitors of polyomavirus replication
D-Scholarship@Pitt (University of Pittsburgh)·2011Open Access
High-Throughput Screening Identifies a Bisphenol Inhibitor of SV40 Large T Antigen ATPase Activity
SLAS DISCOVERY·2011· 14 citedOpen Access
Chemical methodology as a source of small-molecule checkpoint inhibitors and heat shock protein 70 (Hsp70) modulators
Proceedings of the National Academy of Sciences·2011· 74 cited
Inhibition of Simian Virus 40 replication by targeting the molecular chaperone function and ATPase activity of T antigen
Virus Research·2009· 41 citedOpen Access

Frequent Co-authors

Jeffrey L. Brodsky(8), Yoshinari Miyata(4), Jason E. Gestwicki(4), Peter Wipf(4), Umesh K. Jinwal(3), Zapporah T. Young(3), Chad A. Dickey(3), Alex W. Ireland(3), James M. Pipas(3), Jose F. Abisambra(2), Laura J. Blair(2), Xiaokai Li(2), Justin Bacon(2), Sarah Brady(2), Matthew E. Cockman(2), Chantal Guidi(2), John Koren(2), Christopher Atkins(2), Lisa Y. Lawson(2), Edwin J. Weeber(2)