Trevor Broadt

Leidos (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index309citations10works0.02yr avg
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Research Topics

Virus-based gene therapy research(5), Viral Infectious Diseases and Gene Expression in Insects(5), Monoclonal and Polyclonal Antibodies Research(3), CAR-T cell therapy research(3), Viral gastroenteritis research and epidemiology(2)

Publications10 total

Regenerative responses of rabbit corneal endothelial cells to stimulation by fibroblast growth factor 1 (FGF1) derivatives, TTHX1001 and TTHX1114
Growth Factors·2021· 13 citedOpen Access
Detailed Protocol for the Novel and Scalable Viral Vector Upstream Process for AAV Gene Therapy Manufacturing
Human Gene Therapy·2021· 26 citedOpen Access
Safety and Stability of Antibody-Dye Conjugate in Optical Molecular Imaging
Molecular Imaging and Biology·2020· 15 citedOpen Access
Mammalian cell transient expression, non-affinity purification, and characterization of human recombinant IGFBP7, an IGF-1 targeting therapeutic protein
International Immunopharmacology·2015· 7 cited
Clinical manufacturing of recombinant human interleukin 15. I. Production cell line development and protein expression in <i>E. coli</i> with stop codon optimization
Biotechnology Progress·2011· 20 citedOpen Access
A New Generation of Serotype Chimeric Infectivity-Enhanced Conditionally Replicative Adenovirals: The Safety Profile of Ad5/3-Δ24 in Advance of a Phase I Clinical Trial in Ovarian Cancer Patients
Human Gene Therapy·2010· 19 citedOpen Access
Recombinant Oncolytic Poliovirus Eliminates Glioma In Vivo Without Genetic Adaptation to a Pathogenic Phenotype
Molecular Therapy·2008· 83 citedOpen Access
Identifying the safety profile of a novel infectivity-enhanced conditionally replicative adenovirus, Ad5-Δ24-RGD, in anticipation of a phase I trial for recurrent ovarian cancer
American Journal of Obstetrics and Gynecology·2007· 40 cited
Large-Scale Chromatographic Purification of an Attenuated Chimeric Poliovirus
BioProcessing Journal·2005
Preclinical Manufacture of an Anti-HER2 scFv-PEG-DSPE, Liposome-Inserting Conjugate. 1. Gram-Scale Production and Purification
Biotechnology Progress·2005· 86 cited

Frequent Co-authors

Xiaoyi Yang(4), Jianwei Zhu(3), Steven L. Giardina(3), George Mitra(3), John Roach(2), Judith Poiley-Nelson(2), Ray Harris(2), Minghui Wang(2), David T. Curiel(2), Ronald D. Alvarez(2), Asaf Alimardanov(2), Vinay Vyas(2), Dominic Esposito(2), Man‐Shiow Jiang(2), Stephen P. Creekmore(2), Anthony Welch(2), Earl Nelson(2), David F. Nellis(1), D. Ekström(1), Dmitri B. Kirpotin(1)