Stephen M. Dalby

Merck & Co., Inc., Rahway, NJ, USA (United States) — United States

Chemistry · Physical Sciences

28h-index1.9kcitations78works10.52yr avg
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Research Topics

Synthetic Organic Chemistry Methods(41), Marine Sponges and Natural Products(25), Carbohydrate Chemistry and Synthesis(24), Microbial Natural Products and Biosynthesis(11), Crystallization and Solubility Studies(11)

Publications78 total

General chemoselective hindered amide coupling enabled by TCFH-catalytic Oxyma and transient imine protection
Chemical Communications·2024
Evolution of a Green and Sustainable Manufacturing Process for Belzutifan: Part 1─Process History and Development Strategy
Organic Process Research & Development·2024· 21 cited
Novel Analytical Approach to Quantify Reactive Potentially Mutagenic Sulfonate Ester Impurities in Pharmaceutical Compounds and Its Application in the Development of a Control Strategy for Nonaflate Impurities in Belzutifan Synthesis
Organic Process Research & Development·2022· 2 cited
An Investigation into the Unexpected Corrosion of Nickel Alloy Vessels with Selectfluor
Organic Process Research & Development·2021· 5 cited
Manufacturing Process Development for Belzutifan, Part 5: A Streamlined Fluorination–Dynamic Kinetic Resolution Process
Organic Process Research & Development·2021· 42 cited
Manufacturing Process Development for Belzutifan, Part 6: Ensuring Scalability for a Deoxyfluorination Reaction
Organic Process Research & Development·2021· 32 cited
Manufacturing Process Development for Belzutifan, Part 2: A Continuous Flow Visible-Light-Induced Benzylic Bromination
Organic Process Research & Development·2021· 85 cited
Manufacturing Process Development for Belzutifan, Part 4: Nitrogen Flow Criticality for Transfer Hydrogenation Control
Organic Process Research & Development·2021· 26 cited
Manufacturing Process Development for Belzutifan, Part 3: Completing a Streamlined Through-Process with a Safe and Scalable Oxidation
Organic Process Research & Development·2021· 27 cited
Manufacturing Process Development for Belzutifan, Part 1: A Concise Synthesis of the Indanone Starting Material
Organic Process Research & Development·2021· 39 cited
Benzylic Photobromination for the Synthesis of Belzutifan: Elucidation of Reaction Mechanisms Using In Situ LED-NMR
The Journal of Organic Chemistry·2021· 28 cited
Safety Assessments Supporting Scale-up of Chemistry Involving Hydrogen
Organic Process Research & Development·2021· 4 cited
Kilogram-Scale Synthesis of 2′-<i>C</i>-Methyl-<i>arabino</i>-Uridine from Uridine via Dynamic Selective Dipivaloylation
Organic Process Research & Development·2021· 12 cited
Efficient synthesis of antiviral agent uprifosbuvir enabled by new synthetic methods
Chemical Science·2021· 21 citedOpen Access
Asymmetric Synthesis of Letermovir Using a Novel Phase-Transfer-Catalyzed Aza-Michael Reaction
Organic Process Research & Development·2016· 53 cited
ChemInform Abstract: Total Synthesis of Jiadifenolide.
ChemInform·2014
ChemInform Abstract: Total Synthesis of the Antimitotic Marine Macrolide (‐)‐Leiodermatolide.
ChemInform·2014
Total Synthesis of Jiadifenolide
Angewandte Chemie International Edition·2014· 47 citedOpen Access
Total Synthesis of Jiadifenolide
Angewandte Chemie·2014· 7 citedOpen Access
Total Synthesis of the Antimitotic Marine Macrolide (−)‐Leiodermatolide
Angewandte Chemie International Edition·2014· 41 citedOpen Access
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Frequent Co-authors

Ian Paterson(28), Edward A. Anderson(14), Jong Ho Lim(11), Philip Maltas(11), Christian Moessner(8), Julien Genovino(6), Adam J. Fine(5), Jonathan P. McMullen(4), Feng Peng(4), Olivier Loiseleur(4), Tao Wang(4), Rekha Gangam(4), K. C. Nicolaou(3), Lushi Tan(3), Zhiguo J. Song(3), Mengyang Xuan(3), Eric M. Phillips(3), Kerstin Zawatzky(3), Daniel A. DiRocco(3), Jungchul Kim(3)