Hitoshi Shinotoh

National Institutes for Quantum and Radiological Science and Technology — Japan

Medicine · Health Sciences

38h-index6.0kcitations226works8.12yr avg
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Research Topics

Alzheimer's disease research and treatments(66), Parkinson's Disease Mechanisms and Treatments(44), Dementia and Cognitive Impairment Research(42), Medical Imaging Techniques and Applications(42), Cholinesterase and Neurodegenerative Diseases(37)

Publications222 total

Quantification of monoamine oxidase B expression with 11C-SL25.1188 for imaging reactive astrocytes in patients with Alzheimer’s disease
European Journal of Nuclear Medicine and Molecular Imaging·2025Open Access
Topographic Association between Tau Pathology and Atrophy Correlated with Key Symptoms in Progressive Supranuclear Palsy
2025· 1 citedOpen Access
Concurrent Alzheimer's disease pathologies in Lewy body diseases affect cognition and glucose metabolism in the posterior cingulate gyrus: A multimodal PET study
Journal of Alzheimer s Disease·2025· 1 cited
Distinct Tau Pathologies in the Nucleus Basalis of Meynert between Early-Onset and Late-Onset Alzheimer’s Disease Patients Revealed by Positron Emission Tomography
European Psychiatry·2025Open Access
Remote Cortical Network for Frontal Cognitive Symptoms Derived from Tau Accumulation in Progressive Supranuclear Palsy
2025Open Access
IN VIVO CLASSIFICATION OF TAU PATHOLOGIES BY POSITRON EMISSION TOMOGRAPHY IN PATIENTS WITH FRONTOTEMPORAL DEMENTIA
The International Journal of Neuropsychopharmacology·2025Open Access
Diffusion Tensor Image Analysis of Glymphatic Dysfunction in Creutzfeldt-Jakob Disease
Neurology·2024
Distinct tau pathologies in the nucleus basalis of Meynert between early-onset and late-onset Alzheimer's disease patients revealed by positron emission tomography
Journal of Alzheimer s Disease·2024· 2 cited
A novel plasma p-tau181 assay as a specific biomarker of tau pathology in Alzheimer's disease
Translational Neurodegeneration·2024· 9 citedOpen Access
Imaging α-synuclein pathologies in animal models and patients with Parkinson’s and related diseases
Neuron·2024· 76 citedOpen Access
<i>In Vivo</i> Assessment of Astrocyte Reactivity in Patients with Progressive Supranuclear Palsy
Annals of Neurology·2024· 5 citedOpen Access
Misfolded protein deposits in Parkinson’s disease and Parkinson’s disease-related cognitive impairment, a [11C]PBB3 study
npj Parkinson s Disease·2024· 10 citedOpen Access
White Matter Neuroinflammation Matters in Early Alzheimer Disease
Neurology·2024· 2 citedOpen Access
<i>In vivo</i> PET classification of tau pathologies in patients with frontotemporal dementia
Brain Communications·2024· 13 citedOpen Access
Investigating neural dysfunction with abnormal protein deposition in Alzheimer’s disease through magnetic resonance spectroscopic imaging, plasma biomarkers, and positron emission tomography
NeuroImage Clinical·2023· 5 citedOpen Access
Development and Comparison of a Novel Mid‐Region Directed p‐Tau 181 Assay with Tau Positron Emission Tomography in Alzheimer’s Disease
Alzheimer s & Dementia·2023Open Access
The aftermath of boxing: Longitudinal changes of cerebral retention patterns of <sup>18</sup>F‐florzolotau (<sup>18</sup>F‐APN‐1607) in the former professional boxers
Alzheimer s & Dementia·2023· 1 citedOpen Access
<i>In vivo</i> characterization of tau accumulation in patients with frontotemporal dementia: A PET study with <sup>18</sup>F‐florzolotau
Alzheimer s & Dementia·2023Open Access
<i>In vivo</i> assessment of astrocyte reactivity in patients with progressive supranuclear palsy
2023· 1 citedOpen Access
Development and Performance Assessment of a Novel Plasma p-Tau181 Assay Reflecting Tau Tangle Pathology in Alzheimer’s Disease
2023· 1 citedOpen Access
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Frequent Co-authors

Tetsuya Suhara(21), Hitoshi Shimada(17), Toshiaki Irie(17), Kiyoshi Fukushi(14), Makoto Higuchi(12), Shigeki Hirano(11), Noriko Tanaka(11), Akiyo Aotsuka(10), Hiroki Namba(9), Shin‐ichiro Nagatsuka(8), Satoshi Kuwabara(7), Ming‐Rong Zhang(7), Tsuneyoshi Ota(7), Shuji Tanada(7), Maiko Ono(6), Hiroshi Ito(6), Masaomi Iyo(6), Yasuyuki Kimura(6), Osamu Inoue(6), Hironobu Endo(6)