Oriana Bórquez-Ojeda

Memorial Sloan Kettering Cancer Center — United States

Medicine · Health Sciences

13h-index6.9kcitations24works0.02yr avg
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Research Topics

CAR-T cell therapy research(17), Virus-based gene therapy research(5), Acute Lymphoblastic Leukemia research(5), Immunotherapy and Immune Responses(4), Chronic Lymphocytic Leukemia Research(4)

Publications24 total

Depletion of high-content CD14+ cells from apheresis products is critical for successful transduction and expansion of CAR T cells during large-scale cGMP manufacturing
Molecular Therapy — Methods & Clinical Development·2021· 44 citedOpen Access
459. Evaluation of Miltenyi ExpAct and TransAct CD3/28 Beads for CAR-T Cell Manufacturing
Molecular Therapy·2016· 13 citedOpen Access
High-Content CD14+ Cells in Apheresis Products negatively affects the Transduction and Expansion of CAR T cells during Large-scale cGMP Manufacturing
The Journal of Immunology·2016
80. Depletion of High-Content CD14+ Cells from Apheresis Products is Critical for the Successful Transduction and Expansion of CAR T Cells During Large-Scale cGMP Manufacturing
Molecular Therapy·2015· 5 citedOpen Access
Abstract CT102: Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia
Cancer Research·2014· 7 cited
Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic Leukemia
Science Translational Medicine·2014· 2.5k citedOpen Access
Phase I Trial Of Autologous CD19-Targeted CAR-Modified T Cells As Consolidation After Purine Analog-Based First-Line Therapy In Patients With Previously Untreated CLL
Blood·2013· 7 cited
Safe and Effective Re-Induction Of Complete Remissions In Adults With Relapsed B-ALL Using 19-28z CAR CD19-Targeted T Cell Therapy
Blood·2013· 9 cited
CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic Leukemia
Science Translational Medicine·2013· 2.1k citedOpen Access
Molecular Remission and B Cell Aplasia Induced in a First Cohort of Adults with Relapsed B-ALL Treated with 19–28z CAR-Targeted T Cells
Blood·2012· 2 cited
Targeting castration resistant prostate cancer (CRPC) with autologous PSMA-directed CAR+ T cells.
Journal of Clinical Oncology·2012· 7 cited
A phase I clinical trial of autologous, anti-CD19 gene targeted T cells for adults with B cell acute lymphoblastic leukemia (B-ALL).
Journal of Clinical Oncology·2012
Artificial Antigen Presenting Cells Expand NY-ESO-1 Antigen-Specific CD8+ T Cells From Patients with Melanoma
Blood·2011
Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias
Blood·2011· 1.3k citedOpen Access
Manufacturing Validation of Biologically Functional T Cells Targeted to CD19 Antigen for Autologous Adoptive Cell Therapy
Journal of Immunotherapy·2009· 316 citedOpen Access
A phase I trial for the treatment of purine analog-refractory chronic lymphocytic leukemia using autologous T cells genetically targeted to the B cell specific antigen CD19
Journal of Clinical Oncology·2008· 5 cited
Production of clinical-grade plasmid DNA for human Phase I clinical trials and large animal clinical studies
Vaccine·2007· 42 cited
313. Cell Type Specific Media Optimization for Clinical Retroviral Transduction Protocols
Molecular Therapy·2006Open Access
Hydrogen peroxide generated extracellularly by receptor–ligand interaction facilitates cell signaling
Proceedings of the National Academy of Sciences·2005· 156 citedOpen Access
Vitamin C Is a Kinase Inhibitor: Dehydroascorbic Acid Inhibits IκBα Kinase β
Molecular and Cellular Biology·2004· 125 citedOpen Access
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Frequent Co-authors

Isabelle Rivière(18), Michel Sadelain(15), Jolanta Stefanski(14), Shirley Bartido(12), Jinrong Qu(10), Renier J. Brentjens(10), Xiuyan Wang(10), Jae H. Park(8), Clare Taylor(8), Marco L. Davila(7), Malgorzata Olszewska(7), Teresa Wasielewska(7), Qing He(6), David W. Golde(6), Kevin J. Curran(5), Yvette Bernal(5), Mark G. Frattini(5), Mark Przybylowski(5), Juan M. Cárcamo(5), Xiuyan Wang(4)