Zhuyu Peng

Massachusetts Institute of Technology — United States

Neuroscience · Life Sciences

10h-index4.6kcitations13works0.02yr avg
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Research Topics

Neuroinflammation and Neurodegeneration Mechanisms(4), Single-cell and spatial transcriptomics(4), Alzheimer's disease research and treatments(3), CRISPR and Genetic Engineering(2), Tryptophan and brain disorders(2)

Publications13 total

Single-cell atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer’s disease pathology
Cell·2023· 426 citedOpen Access
Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration
Cell·2023· 115 citedOpen Access
Lateral mammillary body neurons in mouse brain are disproportionately vulnerable in Alzheimer’s disease
Science Translational Medicine·2023· 22 citedOpen Access
Revealing nanostructures in brain tissue via protein decrowding by iterative expansion microscopy
Nature Biomedical Engineering·2022· 82 citedOpen Access
Single-cell mosaicism analysis reveals cell-type-specific somatic mutational burden in Alzheimer’s Dementia
2022· 5 citedOpen Access
Single-cell deconvolution of 3,000 post-mortem brain samples for eQTL and GWAS dissection in mental disorders
2021· 15 citedOpen Access
Expansion Revealing: Decrowding Proteins to Unmask Invisible Brain Nanostructures
2020· 24 citedOpen Access
Probing the functions of microglial cyclin-dependent kinase 5 under physiological and pathological conditions
2020Open Access
Author Correction: Single-cell transcriptomic analysis of Alzheimer’s disease
Nature·2019· 61 citedOpen Access
Single-cell transcriptomic analysis of Alzheimer’s disease
Nature·2019· 2.6k citedOpen Access
Single Nuclei RNA Sequencing Reveals Gene Expression Alterations in Alzheimer’s Disease
Brandeis Institutional Repository·2019Open Access
APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types
Neuron·2018· 208 citedOpen Access
APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types
Neuron·2018· 1.1k citedOpen Access

Frequent Co-authors

Li‐Huei Tsai(12), David A. Bennett(7), Manolis Kellis(7), Hansruedi Mathys(6), Fatema Abdurrob(6), José Dávila-Velderrain(4), Fan Gao(4), Jennie Z. Young(4), Xueqiao Jiang(4), Shahin Mohammadi(3), Liang He(3), Jay Penney(3), Hugh P. Cam(3), Carles A. Boix(3), Madhvi Menon(2), Anthony J. Martorell(2), Richard M. Ransohoff(2), Brian P. Hafler(2), Yuan-Ta Lin(2), Jinsoo Seo(2)